Results 81 to 90 of about 47,680 (217)

Are Cochlear Implants Indicated in the Advanced Aging Population?

The Laryngoscope, EarlyView.
India Jackson, Tiffany Peng Hwa, Michael Ruckenstein   +2 more
wiley   +1 more source

Phenotypic Exploration in Patients with Heterozygous Variant in AFG3L2 Gene: A Case‐Series and Literature Review

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Variants in AFG3‐Like Matrix AAA Peptidase, Subunit 2 (AFG3L2) gene are associated with diverse clinical phenotypes. Here, we describe phenotypic findings of two unrelated children with de novo heterozygous variant and one family with inherited heterozygous variant in AFG3L2 gene.
Sangeetha Yoganathan, Laura Tochen, Jacky Ganguly, Sayoni Roy Chowdhury, Haya S AlFaris, Vivek Pai, Andrea LeBlanc‐Millar, Sara Breitbart, Hrishikesh Kumar, Manohar Shroff, Arun Reginald, Grace Yoon, Alfonso Fasano, George M Ibrahim, Carolina Gorodetsky   +14 more
wiley   +1 more source

Longitudinal Cochlear Implant Use in Pediatric Patients With Unilateral Hearing Loss

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To characterize longitudinal cochlear implant (CI) usage patterns in children with unilateral hearing loss (UHL) and evaluate the impact of age at implantation and duration of deafness on device use. Study Design Retrospective cohort study. Setting Two academic tertiary care centers. Methods Pediatric CI recipients with UHL implanted
David Octeau, Gabrielle Watson, Benjamin Wajsberg, Lacey Cantrell, Camille Dunn, Samantha Anne   +5 more
wiley   +1 more source

Determinant of chronic suppurative otitis media and its association with the sensorineural component of hearing loss

Journal of Indira Gandhi Institute of Medical Sciences
Background: Chronic suppurative otitis media (CSOM) is a leading disorder known for hearing loss. We aimed to investigate the associated determinant factors of CSOM with sensorineural hearing loss (SNHL).
Shruti Jha, Rakesh Kumar Singh
doaj   +1 more source

Effects of Asymmetric Auditory Deprivation in Sequential Cochlear Implant

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To evaluate the influence of auditory deprivation on sequential cochlear implants in postlingual patients, comparing the ear with shorter deprivation (ESAD), longer deprivation (ELAD), and the bilateral condition (BIL). Study design Retrospective study. Setting A tertiary referral center.
Eduardo S. Farinazzo, Rubens V. de Brito Neto, Elisabete H. Yamaguti, Marco A. Fornazieri, Luiz F. M. Lourençone   +4 more
wiley   +1 more source

Complications of Cochlear Implant Surgery in Low‐ and Middle‐Income Countries: A Systematic Review

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Hearing loss disproportionately affects low‐ and middle‐income countries (LMICs). Recent advances in cochlear implant surgery have benefitted patients globally, but the risk of complications in LMICs may be heightened due to social and structural factors.
Akash Srinivasan, Anavi Prakash, Wing K. Chou, Kat Steiner, Kokila Lakhoo   +4 more
wiley   +1 more source

Comparison of Hearing Phenotypes Among Children With Congenital Cytomegalovirus and Other Non‐Cytomegalovirus Conditions

OTO Open
Objective Hearing phenotype of the congenital cytomegalovirus (cCMV)‐infected children with isolated sensorineural hearing loss (SNHL) may be distinct from other types of SNHL and may provide an alternative approach for diagnosis.
Shi Liang, Emily Huang, Jordan Stout, Candace Winterton, Chong Zhang, Bridget F. Dorsey, Angela Presson, Matthew Firpo, Albert Park   +8 more
doaj   +1 more source

Scan for Success? Number Needed to Scan and Management Changes in Preoperative Otosclerosis: Quantitative Analysis

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To quantify the cumulative number of images needed to scan (NNS) with preoperative high‐resolution temporal bone computed tomography (HR‐TBCT) to yield a change in management in patients undergoing primary stapes surgery for otosclerosis‐related hearing loss. Study Design Retrospective cohort.
Omer J. Ungar, Adi Brenner, Daniel Zikk, Rani Abu‐Eta, Yahav Oron, Oren Cavel, Ophir Handzel, Nidal Muhanna, Shiri L. Maymon   +8 more
wiley   +1 more source

Jervell and Lange‐Nielsen Syndrome Related Clinical Genetics and Experimental Models

Pediatric Discovery, EarlyView.
ABSTRACT Jervell and Lange‐Nielsen syndrome (JLNS) is defined by electrocardiographic QT prolongation and sensorineural hearing loss, caused by homozygous or compound heterozygous variants in KCNQ1 and/or KCNE1. KCNQ1 encodes the alpha subunit Kv7.1 of the ion channels accountable for slow delayed rectifier potassium currents (IKs), whereas KCNE1 ...
Yafei Zhou, Christopher L.‐H. Huang, Ying Yang, Yanmin Zhang   +3 more
wiley   +1 more source

Monogenic and syndromic obesity in children: Clinical recognition, genetics, and precision management

Pediatric Investigation, EarlyView.
Monogenic and syndromic obesity in children often arises from defects in the leptin–melanocortin pathway. Understanding these rare genetic causes not only clarifies mechanisms of appetite regulation but also enables precision therapies, offering hope beyond lifestyle interventions.
Hadel Khalil, Eugene Feigin, Hussein Zaitoon   +2 more
wiley   +1 more source