Results 61 to 70 of about 161,807 (290)

Prevention of acquired sensorineural hearing loss in mice by in vivo Htra2 gene editing

open access: yesGenome Biology, 2021
Background Aging, noise, infection, and ototoxic drugs are the major causes of human acquired sensorineural hearing loss, but treatment options are limited. CRISPR/Cas9 technology has tremendous potential to become a new therapeutic modality for acquired
Xi Gu   +8 more
semanticscholar   +1 more source

Sensorineural Deafness and MMR Immunization

open access: yesPediatric Neurology Briefs, 1993
Nine reports of sensorineural hearing loss after measles, mumps, and rubella (MMR) immunization were evaluated at the Radcliffe Infirmary, Oxford, England.
J Gordon Millichap
doaj   +1 more source

Sensorineural Deafness in Early Acquired Syphilis [PDF]

open access: yesCanadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, 1983
SUMMARY:A 36 year old male developed bilateral sensorineural deafness as the chief manifestation of secondary syphilis. Cerebrospinal fluid showed pleocytosis. Treatment with penicillin and prednisone resulted in good recovery of hearing. Initial recovery seemed dependent on corticosteroids.
P, Saltiel, C A, Melmed, D, Portnoy
openaire   +2 more sources

Development of the stria vascularis and potassium regulation in the human fetal cochlea : insights into hereditary sensorineural hearing loss [PDF]

open access: yes, 2015
Sensorineural hearing loss (SNHL) is one of the most common congenital disorders in humans, afflicting one in every thousand newborns. The majority is of heritable origin and can be divided in syndromic and nonsyndromic forms. Knowledge of the expression
Chuva de Sousa Lopes, Susana Marina   +5 more
core   +2 more sources

Permanent Sensorineural Deafness in a Patient with Chronic Myelogenous Leukemia Secondary to Intracranial Hemorrhage

open access: yesCase Reports in Hematology, 2013
A 52-year-old male presented with tinnitus and fullness in left ear for one day. Workup revealed a white blood cell count of 685 × 103/μL with marked increase in granulocyte series and myeloid precursors on peripheral smear.
Sakshi Kapur   +3 more
semanticscholar   +1 more source

Compensatory Interplay Between Clarin‐1 and Clarin‐2 Deafness‐Associated Proteins Governs Phenotypic Variability in Hearing

open access: yesAdvanced Science, EarlyView.
Functional compensation between clarin‐1 and clarin‐2 in cochlear hair cells. Hearing loss associated with CLRN1 mutations shows striking phenotypic variability; however, the underlying mechanisms remain poorly understood. This study reveals that clarin‐1 and clarin‐2 function cooperatively in cochlear hair cells to sustain mechanoelectrical ...
Maureen Wentling   +17 more
wiley   +1 more source

Compound heterozygous dominant and recessive GJB2 mutations cause deafness with palmoplantar keratoderma

open access: yesActa Oto-Laryngologica Case Reports, 2017
GJB2 gene mutation is the most common cause of congenital sensorineural hearing loss worldwide. Most GJB2 gene mutations have been associated with autosomal recessive non-syndromic hearing loss (DFNB1), but some are also associated with autosomal ...
Yasuhiro Arai   +5 more
doaj   +1 more source

Characteristics of Mid-Frequency Sensorineural Hearing Loss Progression. [PDF]

open access: yes, 2019
OBJECTIVES:To characterize the progression of mid-frequency sensorineural hearing loss (MFSNHL) over time. METHODS:A retrospective chart review spanning 2012 to 2017 was performed at a tertiary care audiology and neurotology center.
Abouzari, Mehdi   +9 more
core   +2 more sources

Optimal management of Cogan’s syndrome: a multidisciplinary approach [PDF]

open access: yes, 2017
Cogan's syndrome (CS) is a rare disorder characterized by nonsyphilitic interstitial keratitis (IK) and audio-vestibular symptoms. CS affects mainly young Caucasian adults, mostly during their first three decades of age, and may develop into typical and ...
D'Aguanno, Vittorio   +3 more
core   +1 more source

Congenital Sensorineural Deafness in Dalmatian Dogs Associated with Quantitative Trait Loci

open access: yesPLoS ONE, 2013
A genome-wide association study (GWAS) was performed for 235 Dalmatian dogs using the canine Illumina high density bead chip to identify quantitative trait loci (QTL) associated with canine congenital sensorineural deafness (CCSD).
Susanne Kluth, O. Distl
semanticscholar   +1 more source

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