Results 71 to 80 of about 31,332 (279)

Small Extracellular Vesicles Orchestrate Cisplatin‐Induced Ototoxicity: Potential Biomarker and Targets Discovery

open access: yesAdvanced Science, EarlyView.
Cisplatin causes reactive oxygen species accumulation, leading to apoptosis and inflammation in cochlear hair cells. Small extracellular vesicles primarily derived from the damaged hair cells likely contribute to cisplatin‐induced ototoxicity, carrying a variety of microRNAs and proteins.
Jingru Ai   +14 more
wiley   +1 more source

RISIKO GANGGUAN PENDENGARAN PADA NEONATUS HIPERBILIRUBINEMIA [PDF]

open access: yes, 2010
Background. The prevalence of hearing impairment on the Indonesian population according to 2007 WHO data is estimated at 4.2 %, and one of the cause is neonatal hyperbilirubinemia.
Susanto, Susanto
core  

Risk factors for sensorineural hearing loss among high-risk infants in Golestan province, Iran in 2010 - 2011 [PDF]

open access: yes, 2015
Background: Hearing impairment, as one of the most common birth defects, is a hidden disability with negative impacts on speech and cognitive development. Objectives: The aim of this study was to assess the prevalence of sensorineural hearing loss (SNHL)
Alaee, E.   +3 more
core   +2 more sources

Visualization of the Spiral Ganglion Neuron in Vivo Using a Novel 177Lu Nuclear Molecule Label

open access: yesAdvanced Science, EarlyView.
The study developed and validated a radionuclide‐labeled anti‐VGLUT1 antibody probe for the first nuclear imaging of cochlear spiral ganglion neurons (SGNs) in vivo. This approach may provide aid in screening candidates suitable for CI surgery by quantifying the number of surviving SGNs, and predicting the potential for postoperative hearing ...
Chenyang Kong   +11 more
wiley   +1 more source

Audiogenic reflex seizures in cats [PDF]

open access: yes, 2015
This study aims at characterizing feline audiogenic reflex seizures (FARS). An online questionnaire was developed to capture information from owners with cats suffering FARS.
Bessant, C   +4 more
core   +2 more sources

Chromosome 3q22.2‐q26.2 Interstitial Deletion in a Patient With Wisconsin Syndrome, Blepharophimosis‐Ptosis‐Epicanthus Inversus Syndrome, Dandy‐Walker Malformation, Pierre Robin Sequence, and Recurrent Infections

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Wisconsin syndrome is a very rare genetic condition characterized by coarse facies, prominent nasal tip, bushy high arched/upsweeping eyebrows, and a full/everted lower lip. Deletion of chromosome 3q24q25 region is considered critical for its manifestation.
Pankaj Prasun   +2 more
wiley   +1 more source

Eeyore: a novel mouse model of hereditary deafness. [PDF]

open access: yesPLoS ONE, 2013
Animal models that recapitulate human disease are proving to be an invaluable tool in the identification of novel disease-associated genes. These models can improve our understanding of the complex genetic mechanisms involved in disease and provide a ...
Kerry A Miller   +3 more
doaj   +1 more source

DPOAE in HIV infected adults [PDF]

open access: yes, 2008
HIV infection is associated with impairment of hearing function, at any stage of disease causing complication to the external, middle, inner ear and CNS.
Bhat, Jayashree S, Ranjan, Rajesh
core  

Effects of cochlear implantation on binaural hearing in adults with unilateral hearing loss [PDF]

open access: yes, 2018
A FDA clinical trial was carried out to evaluate the potential benefit of cochlear implant (CI) use for adults with unilateral moderate-to-profound sensorineural hearing loss.
Brown, Kevin D   +7 more
core   +2 more sources

A novel transgenic reporter of extracellular acidification in zebrafish elucidates skeletal muscle T‐tubule pH regulation

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Disruption of extracellular pH and proton‐sensing can profoundly impact cellular and protein functions, leading to developmental defects. To visualize changes in extracellular pH in the developing embryo, we generated a zebrafish transgenic line that ubiquitously expresses the ratiometric pH‐sensitive fluorescent protein pHluorin2, tethered to
Leif R. Neitzel   +5 more
wiley   +1 more source

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