Results 231 to 240 of about 166,190 (339)

Impact of the ACEMg Biomedicine on Sensorineural Hearing Loss and Auditory Function: Analysis of Real-World Clinical Data

Barry Seifer, Richard Detweiler, Louise A Minor   +2 more
openalex   +2 more sources

Novel Pathogenic Variant Confirms the Association of REST and Jones Syndrome

Clinical Genetics, Volume 109, Issue 1, Page 199-203, January 2026.
Jones syndrome (JS) is an ultra‐rare condition characterized by gingival fibromatosis and progressive sensorineural hearing loss. It has been associated with a pathogenic REST exon‐5 variant (c.2670_2673del) in a Finnish family. We describe the first Italian family with JS in which a novel pathogenic REST exon‐5 variant (c.2645T>G) was identified ...
Valentina Lodato, Massimo Galli, Giacomo D'Angeli, Irene Bottillo, Luca Celli, Rosaria Turchetta, Andrea Colizza, Francesca Gianno, Biagio Palmisano, Francesca Romana Federici Stanganelli, Maria Rita Bianco, Daniela Messineo, Eugenia Allegra, Paola Grammatico, Mara Riminucci, Alessandro Corsi   +15 more
wiley   +1 more source

Hyperbaric oxygen therapy for sudden sensorineural hearing loss (Review). [PDF]

Mol Med Rep
Sun Y, Wang S, Fu H, Ge X, Pan S.
europepmc   +1 more source

Single‐Nucleus Transcriptomics Uncovers Xaf1‐Driven PANoptosis as a Therapeutic Target in Aminoglycoside‐Induced Hearing Loss

Cell Proliferation, Volume 59, Issue 1, January 2026.
Neomycin induces increased expression of Xaf1 in cochlear HCs, triggering PANoptosis, which encompasses pyroptosis, apoptosis and necroptosis (left). Targeted Xaf1 knockdown in HCs through gene therapy can significantly inhibit the occurrence of PANoptosis in HCs (right).
Xinlin Wang, Hairong Xiao, Jiheng Wu, Yanqin Lin, Yiheng Ao, Zixuan Ye, Xin Tan, Fanliang Kong, Xin Chen, Renjie Chai, Shasha Zhang   +10 more
wiley   +1 more source

Biallelic MINAR2 variant is associated with nonsyndromic severe to profound sensorineural hearing loss. [PDF]

Hum Genome Var
Almontashiri NAM.
europepmc   +1 more source

New cases of δ‐aminolevulinic acid dehydratase deficiency: Functional insights into gene variants using an innovative mouse liver model

Journal of Internal Medicine, Volume 299, Issue 1, Page 126-142, January 2026.
Abstract Background Dysfunction of δ‐aminolevulinic acid dehydratase (ALAD), the second enzyme involved in heme biosynthesis, leads to two pathologies: genetic and acquired. The genetic form is an ultrarare, severe childhood‐onset disease inherited in an autosomal recessive manner, whereas the acquired form usually affects adults due to enzyme ...
Elena Di Pierro, Isabel Solares, Daniel Jericó, Francisco J. Castelbón, Javier Tomás Solera, Antoni Riera‐Mestre, María Barreda‐Sánchez, Carlo Poci, Annamaria Nicolli, Francesco Urigo, Ana Sampedro, Rafael Enríquez de Salamanca, Matteo Marcacci, Matías A. Ávila, Pauline Harper, Marta G. Fanlo‐Maresma, Encarna Guillén‐Navarro, Giovanna Graziadei, Andrea Wenzel, Bodo B. Beck, Paolo Ventura, Montserrat Morales‐Conejo, Antonio Fontanellas   +22 more
wiley   +1 more source

Adriamycin nephropathy induces sensorineural hearing loss via blood-labyrinth barrier breakdown in BALB/c mice. [PDF]

Sci Rep
Gajbhiye A, Jin S, Lyu AR, Kim SJ, Kim TH, Shin SA, Huh YH, Je A, Sohrabji F, Park MJ, Park YH.   +10 more
europepmc   +1 more source

Emerging Therapies for Sensorineural Hearing Loss.

Otology and Neurotology, 2017
Matthew G. Crowson, R. Hertzano, D. Tucci   +2 more
semanticscholar   +1 more source

From Sound to Silence: Cerebellar Abscesses and Herniation Due to Cochlear Implant Infection With Escherichia coli and Bacteroides fragilis

Case Reports in Infectious Diseases, Volume 2026, Issue 1, 2026.
Cochlear implantation (CI) is a safe and well‐established intervention for sensorineural hearing loss, with a low incidence of severe postoperative infections. We present the first reported case of cerebellar abscess and herniation due to CI infection. This unique case involves a 57‐year‐old man with recurrent cochlear implant infections, necessitating
Celine Molfetta, Ruchi Biswas, Marc Pickard, Tanzila Salim, Carlos Nuñez, Dawei Cui   +5 more
wiley   +1 more source

A novel audiogram model for predicting the prognosis of sudden sensorineural hearing loss. [PDF]

J Chin Med Assoc
Tseng HW, Hsu CY, Chen CH, Chu YC, Liao WH.   +4 more
europepmc   +1 more source