Results 71 to 80 of about 30,581 (134)
Characteristics of Mid-Frequency Sensorineural Hearing Loss Progression. [PDF]
OBJECTIVES:To characterize the progression of mid-frequency sensorineural hearing loss (MFSNHL) over time. METHODS:A retrospective chart review spanning 2012 to 2017 was performed at a tertiary care audiology and neurotology center.
Abouzari, Mehdi+9 more
core +2 more sources
Abstract Objective The minimal clinically important difference (MCID) represents the smallest change in treatment outcome deemed clinically meaningful. This study estimates the MCID for 2 widely used tinnitus measures: the Tinnitus Handicap Inventory (THI) and the Tinnitus Functional Index (TFI), using anchor‐based approaches while accounting for ...
Milena Engelke+11 more
wiley +1 more source
Neonatal hearing screening in high-risk patients with otoacoustic emissions: evaluation of results [PDF]
Resumen Objetivo: evaluar la efectividad del programa de tamizaje auditivo del Homic en pacientes de alto riesgo de hipoacusia neurosensorial, el cual está basado en la realización de otoemisiones acústicas Diseño: estudio de cohorte retrospectiva, en ...
Diaz Patiño, Diana Patricia+6 more
core
Abstract Objective Increased hours of cochlear implant (CI) use have been shown to improve auditory and speech recognition outcomes in children with hearing loss. However, the impact of hours of CI use over time on patient‐reported functional hearing skills is unknown.
Lacey Magee+3 more
wiley +1 more source
Abstract Objective Spontaneous cerebrospinal fluid (sCSF) leaks of lateral skull base have little consensus on optimal management. We synthesized and evaluated current literature via systematic and meta‐analysis to compare the success rates and complications of the different surgical techniques for middle cranial fossa (MCF) sCSF leak repair.
Dimitrios Spinos+9 more
wiley +1 more source
Patterns of Teprotumumab‐Induced Hearing Dysfunction: A Systematic Review
Abstract Objective Hearing loss has been reported after administration of the monoclonal antibody teprotumumab. The purpose of this study was to review available evidence regarding the patterns of teprotumumab‐related ototoxicity. Data Sources PubMed, EMBASE, and Cochrane Library.
Kevin Wong+8 more
wiley +1 more source
Aminoisothiazolamides, a new class of potent inhibitors of lysyl‐tRNA synthetase
The present work covers a series of novel herbicidal lead structures that possess an aminoisothiazolamide scaffold as a structural key feature. Lysyl‐tRNA synthetase 1 (KRS1) was identified as the biochemical mode‐of‐action. Based on optimized and tailored synthetic approaches, a broader SAR study was carried out delivering some lead structures that ...
David Bernier+26 more
wiley +1 more source
Otosclerosis associated with type B-1 inner ear malformation [PDF]
Malformations of bony inner ear are rare anomalies occurring in approximately 20% of patients with congenital sensorineural hearing loss. Conductive hearing loss is usually associated with abnormalities of the external and middle ear.
Aggarwal N.+3 more
core
Update on Gene Therapy in the Treatment of Hereditary Hearing Loss
Gene therapy is a promising therapeutic approach for genetic disorders, including three major gene therapy strategies: gene replacement, gene suppression, and gene editing. After transmitting genes to the inner ear through appropriate pathways, repair the cochlea in order to achieve the goal of treating hereditary hearing loss.
Weiwei He+7 more
wiley +1 more source
Hearing and communication self-efficacy in adult hearing aid users and non-users with acquired sensorineural hearing loss [PDF]
The purpose of this research study is to determine if differences in hearing and communication self-efficacy exist between adult hearing aid users and non-hearing aid users with acquired sensorineural hearing loss.
Hunt, Ali Christina Mercedes
core +1 more source