Results 161 to 170 of about 499,689 (285)

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Effect of Aging on Motor Inhibition during Action Preparation under Sensory Conflict. [PDF]

Front Aging Neurosci, 2016
Duque J, Petitjean C, Swinnen SP.
europepmc   +1 more source

Epistemic Relativism and Pluralism [PDF]

, 2017
A Koyré, B Barnes, BC Fraassen van, C Wright, G Gutting, G Santillana de, H Dreyfus, JL Heilbron, M Biagioli, M Biogioli, M Kusch, M Seidel, MA Finocchiaro, MA Finocchiaro, P Boghossian, R Redondi, R Rorty, St Drake, WA Wallace, WP Alston   +19 more
core   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Effects of Altered Haptic Feedback Gain Upon Balance Are Explained by Sensory Conflict Estimation. [PDF]

Eur J Neurosci
Reynolds RF, Smith CP, Assländer L.
europepmc   +1 more source

EEG Mapping during Quiet and Sensory-Conflicted Stance [PDF]

, 2015
Bozhidar Dimitrov, Katerina Stambolieva, Plamen Gatev   +2 more
openaire   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

EEG Sources during Quiet and Sensory-Conflicted Stance [PDF]

, 2015
Plamen Gatev, Katerina Stambolieva, Jordanka Lalova, Bozhidar Dimitrov   +3 more
openaire   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source