Results 81 to 90 of about 499,689 (285)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Simulator Sickness within the Framework of the Level Theory of Movement Regulation: Empirical Study

Национальный психологический журнал
Background. Virtual reality (VR) technologies are being applied in various areas of human activity. However, their use is often associated with the onset of simulator sickness. To date, there is no consensus on the mechanisms behind this disorder and the
Elizaveta G. Luniakova , Arina R. Raximova , Margarita D. Belousova   +2 more
doaj   +1 more source

A conflict between spatial selection and evidence accumulation in area LIP

Nature Communications, 2022
In primate area LIP, target selection and the accumulation of sensory evidence are considered a single process. Here, the authors use urgent choice tasks to show that spatial selection in LIP is distinct from, and may even conflict with, evidence ...
Joshua A. Seideman, Terrence R. Stanford, Emilio Salinas   +2 more
doaj   +1 more source

Light Dominates Peripheral Circadian Oscillations in Drosophila melanogaster During Sensory Conflict [PDF]

Journal of Biological Rhythms, 2017
In Drosophila, as in other animals, the circadian clock is a singular entity in name and concept only. In reality, clock functions emerge from multiple processes and anatomical substrates. One distinction has conventionally been made between a central clock (in the brain) and peripheral clocks (e.g., in the gut and the eyes).
Harper, Ross E. F., Ogueta, Maite, Dayan, Peter, Stanewsky, Ralf, Albert, Joerg T.   +4 more
openaire   +4 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

What is embodiment? a psychometric approach [PDF]

, 2008
What is it like to have a body? The present study takes a psychometric approach to this question. We collected structured introspective reports of the rubber hand illusion, to systematically investigate the structure of bodily self-consciousness ...
Aglioti, Armel, Arzy, Austen, Bell, Berlucchi, Bermúdez, Boring, Bottini, Botvinick, Cassam, Costantini, Critchley, Critchley, Damasio, de Vignemont, Durgin, Edelman, Ehrsson, Ehrsson, Ehrsson, Farnè, Friederike Schüür, Gallagher, Gallagher, Gallagher, Gallagher, Ghilardi, Haggard, Hair, Head, Holmes, Jackson, James, James, Jeannerod, Johnson, Kanayama, Kant, Lakoff, Legrand, Manos Tsakiris, Marjolein P.M. Kammers, Matthew R. Longo, McCabe, McGonigle, Meltzoff, Merleau-Ponty, Nunnally, Oldfield, Page, Patrick Haggard, Pavani, Peled, Piaget, Poeck, Press, Putnam, Rode, Rolls, Rorden, Sato, Schaefer, Searle, Sierra, Stevens, Tsakiris, Tsakiris, Tsakiris, Tsakiris, Walton, Witmer   +71 more
core   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Alice in wonderland syndrome. a clinical and pathophysiological review [PDF]

, 2016
Alice in Wonderland Syndrome (AIWS) is a perceptual disorder, principally involving visual and somesthetic integration, firstly reported by Todd, on the literary suggestion of the strange experiences described by Lewis Carroll in Alice in Wonderland ...
DI PIERO, Vittorio, Mancini, Valentina, Mastria, Giulio, Vigano', Alessandro   +3 more
core   +3 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

The Impact of Virtual Reality Content Characteristics on Cybersickness and Head Movement Patterns

Sensors
Virtual reality (VR) technology has gained popularity across various fields; however, its use often induces cybersickness, characterized by symptoms such as dizziness, nausea, and eye strain.
Seo-Yoon Park, Dong-Kyun Koo
doaj   +1 more source