Results 51 to 60 of about 951,101 (178)

Prostaglandin E2 depolarises sensory axons in vitro in an ANO1 and Nav1.8 dependent manner

Scientific Reports
Prostaglandin E2 (PGE2) is a major contributor to inflammatory pain hyperalgesia, however, the extent to which it modulates the activity of nociceptive axons is incompletely understood.
Georgios Kimourtzis, Natasha Rangwani, Bethan J. Jenkins, Siddharth Jani, Peter A. McNaughton, Ramin Raouf   +5 more
doaj   +1 more source

A Network Analysis Approach to Detect and Differentiate Usher Syndrome Types Using miRNA Expression Profiles: A Pilot Study

BioMedInformatics
Background: Usher syndrome (USH) is a rare genetic disorder that affects both hearing and vision. It presents in three clinical types—USH1, USH2, and USH3—with varying onset, severity, and disease progression.
Rama Krishna Thelagathoti, Wesley A. Tom, Chao Jiang, Dinesh S. Chandel, Gary Krzyzanowski, Appolinaire Olou, Rohan M. Fernando   +6 more
doaj   +1 more source

Machine Learning-Based Ensemble Feature Selection and Nested Cross-Validation for miRNA Biomarker Discovery in Usher Syndrome

Bioengineering
Usher syndrome (USH) is a rare genetic disorder affecting vision, hearing, and balance. Identifying reliable biomarkers is crucial for early diagnosis and understanding disease mechanisms.
Rama Krishna Thelagathoti, Dinesh S. Chandel, Wesley A. Tom, Chao Jiang, Gary Krzyzanowski, Appolinaire Olou, M. Rohan Fernando   +6 more
doaj   +1 more source

Comparing Taste Detection Thresholds across Individuals Following Vegan, Vegetarian, or Omnivore Diets

Foods, 2021
Taste perception plays an undisputed role in food choice, preference, and intake. Recent literature suggests that individual diet and taste sensitivity may have a reciprocal relationship, with evidence highlighting that specific diets can alter taste ...
Fatemeh Jalil Mozhdehi, Sashie Abeywickrema, Phil James Bremer, Mei Peng   +3 more
doaj   +1 more source

Event-related brain potential correlates of human auditory sensory memory-trace formation [PDF]

, 2005
The event-related potential (ERP) component mismatch negativity (MMN) is a neural marker of human echoic memory. MMN is elicited by deviant sounds embedded in a stream of frequent standards, reflecting the deviation from an inferred memory trace of the ...
Baldewig, T., Vernon, D., Dwivedi, P, Baldeweg, Torsten, Gruzelier, JH, Dwivedi, Prabuddh, Dwivedi, P., Gruzelier, J., Vernon, DJ, Haenschel, C., Vernon, David J., Baldeweg, T, Gruzelier, John, Haenschel, C, Haenschel, Corinna   +14 more
core   +1 more source

Inhibition of Thioredoxin Reductase Activity and Oxidation of Cellular Thiols by Antimicrobial Agent, 2-Bromo-2-nitro-1,3-propanediol, Causes Oxidative Stress and Cell Death in Cultured Noncancer and Cancer Cells

Biology
Background: The thioredoxin system (TrxS) is crucial for maintaining redox balance by regulating cellular thiol levels and is involved in various biological processes, including cancer progression.
Chao Jiang, Gary Krzyzanowski, Dinesh S. Chandel, Wesley A. Tom, Nirmalee Fernando, Appolinaire Olou, M. Rohan Fernando   +6 more
doaj   +1 more source

Connectomics of the zebrafish's lateral-line neuromast reveals wiring and miswiring in a simple microcircuit

eLife, 2018
The lateral-line neuromast of the zebrafish displays a restricted, consistent pattern of innervation that facilitates the comparison of microcircuits across individuals, developmental stages, and genotypes.
Eliot Dow, Adrian Jacobo, Sajjad Hossain, Kimberly Siletti, A J Hudspeth   +4 more
doaj   +1 more source

Failure of preventive treatments in migraine: an observational retrospective study in a tertiary headache center

BMC Neurology, 2020
Background Although the criteria for acute migraine treatment and prevention have been well described, there are still unmet needs, general underuse and low benefits of preventive drugs.
Marianna Delussi, Eleonora Vecchio, Giuseppe Libro, Silvia Quitadamo, Marina de Tommaso   +4 more
doaj   +1 more source

Diagram for Neuroscience journal article [PDF]

, 2018
A new hypothesis relating ADHD and mind wandering, was published as a journal article 'Mind wandering perspective on attention-deficit/hyperactivity disorder'.
Bozhilova, Natali Stanimirova, Bozhilova, Natali, Michelini, Giorgia; id_orcid, Michelini, G, Kuntsi, Jonna; id_orcid, Asherson, P, Bozhilova, NS, Tan, Kai Syng, Kuntsi, J, Asherson, Philip; id_orcid   +9 more
core   +1 more source

Endothelial dysfunction in idiopathic sudden sensorineural hearing loss: a review

Audiology Research, 2016
An endothelial dysfunction has been described in idiopathic sudden sensorineural hearing loss (ISSHL) patients. The purpose of our review was to: i) identify, evaluate and review recent research about cardiovascular risk factors involvement and signs of ...
Nicola Quaranta, Vincenzo De Ceglie, Alessandra D’Elia   +2 more
doaj   +1 more source