Results 121 to 130 of about 6,295,293 (305)

Sensory Discrimination Tests and Measurements Sensometrics in Sensory Evaluation

, 2015
Sensory testing and measurement are the main functions of sensory analysis. In recent years, the sensory and consumer field has evolved to include both difference testing and similarity testing, and new sensory discrimination methods such as the tetrads ...
Bi, Jian
core  

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Influence of Genotype Lines, Age at Slaughter and Sexes on the Composition of Rabbit Meat

Food Technology and Biotechnology, 2006
Chemical composition (water, proteins, ash, intramuscular fat, cholesterol, fatty acid composition), sensory characteristics and instrumental profiles (colour and texture) of lean rabbit meat were investigated.
Tomaž Polak, Lea Gašperlin, Alenka Rajar, Božidar Žlender   +3 more
doaj  

Sensory vs instrumental analysis for the shelf-life definition of minimally processed vegetables

, 2018
Minimally processed vegetables are fresh vegetables processed to increase their functionality without greatly changing their fresh-like properties. The type of process is dependent on the type of produce and includes all the operations necessary to ...
E. Dellacassa, M. Merlino, A. Verzera, G. Tripodi, F. Cincotta, C. Condurso   +5 more
core   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

A functional role for small-conductance calcium-activated potassium channels in sensory pathways including nociceptive processes [PDF]

, 2005
We investigated the role of small-conductance calcium-activated potassium (SK) and intermediate-conductance calcium-activated potassium channels in modulating sensory transmission from peripheral afferents into the rat spinal cord.
Jowett, AJ, Bahia, PK, Benton, DCH, Moss, GWJ, Suzuki, R, Chen, MX, Trezise, DJ, Dickenson, AH   +7 more
core  

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Exploring the relationship between physical properties and sensory characteristics of newly developed white breads with improved nutritional composition – initial insights [PDF]

Staple foods such as bread are key contributors to the diet. Accordingly, there is growing emphasis on improving the nutritional composition of wheat (e.g., increasing the dietary fibre content); however, the impacts of such improvements on bread ...
Charlton, M., Lignou, S, Wagstaff, Carol, Charlton, Mark, Gillett, Nicola, Shewry, P. R., Lovegrove, A., Prins, Anneke, Wagstaff, C., Rodriguez-Garcia, J., Prins, A., Lovegrove, Alison, Lignou, Stella, Shewry, Peter, Tindall, Marcus, Gillett, N., Norton, Victoria, Rodriguez Garcia, Julia, Norton, V.   +18 more
core   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source