Results 141 to 150 of about 303,068 (314)

P2X₃ Knock-Out Mice Reveal a Major Sensory Role for Urothelially Released ATP

, 2001
The present study explores the possible involvement of a purinergic mechanism in mechanosensory transduction in the bladder using P2X₃ receptor knock-out (P2X₃ ⁻⁄⁻) and wild-type control (P2X₃ ⁺⁄⁺) mice.
Bodin, P, Cockayne, DA, Kasakov, L, Burnstock, G, Rong, W, Bardini, M, Ford, APDW, Vlaskovska, M   +7 more
core  

Nutritional Quality, Potential Health Promoting Properties and Sensory Perception of an Improved Gluten Free Bread Formulation Containing Inulin, Rice Protein and Bioactive Compounds Extracted from Coffee Byproducts

, 2019
The present study aimed to improve the formulation of a gluten-free commercial bread-making premix by adding inulin, rice protein and extracts of coffee by-products (silverskin and husk) to obtain healthier products enriched in protein and dietary fiber ...
Alessandro Guglielmetti, Dolores del Castillo, Giuseppe Zeppa, Beatriz Fernandez-Gomez   +3 more
core   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

A functional role for small-conductance calcium-activated potassium channels in sensory pathways including nociceptive processes

, 2005
We investigated the role of small-conductance calcium-activated potassium (SK) and intermediate-conductance calcium-activated potassium channels in modulating sensory transmission from peripheral afferents into the rat spinal cord.
Jowett, AJ, Bahia, PK, Benton, DCH, Moss, GWJ, Suzuki, R, Chen, MX, Trezise, DJ, Dickenson, AH   +7 more
core  

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

The Role of Sensory Experiences and Information on the Willingness to Pay for Organic Wheat Bread

This study examined the size and the determinants of the price premium a sample of Edmonton-area consumers was willing to pay for organic wheat bread.
Wismer, Wendy V., Boxall, Peter C., Muralidharan, Vijay, Annett, Lisa E., Cash, Sean B.   +4 more
core  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Sugar cane spirits: cachaca and rum production and sensory properties

, 2012
The production of cachaca, a distilled spirit made directly from sugar cane juice and rum obtained by fermenting molasses, a by-product of the sugar industry, are comparatively presented.
Piggott, J., Faria, J. B.
core  

Preliminary study on the development of an antistretch marks water-in-oil cream: ultrasound assessment, texture analysis, and sensory analysis

Clinical, Cosmetic and Investigational Dermatology, 2016
Cătălina Bogdan,1 Mirela L Moldovan,1 Ioana Manuela Man,2 Maria Crișan,2 1Department of Dermopharmacy and Cosmetics, Faculty of Pharmacy, 2Department of Histology, Faculty of Medicine, University of Medicine and Pharmacy “Iuliu Hațieganu&rdquo ...
Bogdan C, Moldovan ML, Man IM, Crișan M
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