Results 151 to 160 of about 23,867,032 (414)

Prepontine non-giant neurons drive flexible escape behavior in zebrafish [PDF]

open access: yes, 2019
Many species execute ballistic escape reactions to avoid imminent danger. Despite fast reaction times, responses are often highly regulated, reflecting a trade-off between costly motor actions and perceived threat level.
Bergeron, S.   +4 more
core   +2 more sources

Targeting rapid TKI‐induced AXL upregulation overcomes adaptive ERK reactivation and exerts antileukemic effects in FLT3/ITD acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale   +9 more
wiley   +1 more source

Correction to: Divergence in chondrogenic potential between in vitro and in vivo of adipose- and synovial-stem cells from mouse and human

open access: yesStem Cell Research & Therapy, 2021
Ryota Chijimatsu   +17 more
doaj   +1 more source

Proprioceptive dysfunction in focal dystonia: from experimental evidence to rehabilitation strategies.

open access: yesFrontiers in Human Neuroscience, 2014
Dystonia has historically been considered a disorder of the basal ganglia, mainly affecting planning and execution of voluntary movements. This notion comes from the observation that most lesions responsible for secondary dystonia involve the basal ...
Laura eAvanzino, Mirta eFiorio
doaj   +1 more source

Transcriptome Pyrosequencing of the Parasitoid Wasp Cotesia vestalis: Genes Involved in the Antennal Odorant-Sensory System

open access: yesPLoS ONE, 2012
Cotesia vestalis is an endoparasitic wasp that attacks larvae of the diamondback moth (Plutella xylostella), a herbivore of cruciferous plants. Females of C. vestalis use herbivore-induced plant odorants released from plants infested by P.
Osamu Nishimura   +4 more
semanticscholar   +1 more source

Integrative systems‐level analysis reveals a contextual crosstalk between hypoxia and global metabolism in human breast tumors

open access: yesMolecular Oncology, EarlyView.
Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam   +2 more
wiley   +1 more source

The Sensory Input from the External Cuneate Nucleus and Central Cervical Nucleus to the Cerebellum Refines Forelimb Movements

open access: yesCells
Goal-directed reaching movements are extremely accurate to the point that the location, placement, and speed of the limbs are specific from trial to trial.
Chidubem Eneanya, George M. Smith
doaj   +1 more source

Mechanisms Underlying the Environmentally Induced Plasticity of Leaf Morphology

open access: yesFrontiers in Genetics, 2018
The primary function of leaves is to provide an interface between plants and their environment for gas exchange, light exposure and thermoregulation. Leaves have, therefore a central contribution to plant fitness by allowing an efficient absorption of ...
Michael André Fritz   +3 more
doaj   +1 more source

Identification of dividing, determined sensory neuron precursors in the mammalian neural crest [PDF]

open access: yes, 1999
Sensory and autonomic neurons of the vertebrate peripheral nervous system are derived from the neural crest. Here we use the expression of lineage-specific transcription factors as a means to identify neuronal subtypes that develop in rat neural crest ...
Anderson, David J.   +2 more
core  

Genetic Architecture of Variation in the Lateral Line Sensory System of Threespine Sticklebacks

open access: yesG3: Genes, Genomes, Genetics, 2012
Vertebrate sensory systems have evolved remarkable diversity, but little is known about the underlying genetic mechanisms. The lateral line sensory system of aquatic vertebrates is a promising model for genetic investigations of sensory evolution because
A. Wark   +11 more
semanticscholar   +1 more source

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