Results 151 to 160 of about 526,955 (247)

Ordered patterning of the sensory system is susceptible to stochastic features of gene expression. [PDF]

Elife, 2020
Giri R, Papadopoulos DK, Posadas DM, Potluri HK, Tomancak P, Mani M, Carthew RW.   +6 more
europepmc   +1 more source

Difficulties of the tactile sensory system sensory integration of children with autism

, 2022
Naim Salkić, Zulfo Ahmetović, Safet Velić, Lara Krnojelac   +3 more
openalex   +2 more sources

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Biomimetic Neuromorphic Sensory System via Electrolyte Gated Transistors. [PDF]

Sensors (Basel)
Li S, Gao L, Liu C, Guo H, Yu J.
europepmc   +1 more source

TREX1, a predator for treating MSI‐H tumors?

Molecular Oncology, EarlyView.
Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya, Joséphine Deneft, Marc Van den Eynde   +2 more
wiley   +1 more source

A Multifunctional Tactile Sensory System for Robotic Intelligent Identification and Manipulation Perception. [PDF]

Adv Sci (Weinh)
Jiang Y, Fan L, Sun X, Luo Z, Wang H, Lai R, Wang J, Gan Q, Li N, Tian J.   +9 more
europepmc   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Inner ear sensory system changes as extinct crocodylomorphs transitioned from land to water. [PDF]

Proc Natl Acad Sci U S A, 2020
Schwab JA, Young MT, Neenan JM, Walsh SA, Witmer LM, Herrera Y, Allain R, Brochu CA, Choiniere JN, Clark JM, Dollman KN, Etches S, Fritsch G, Gignac PM, Ruebenstahl A, Sachs S, Turner AH, Vignaud P, Wilberg EW, Xu X, Zanno LE, Brusatte SL.   +21 more
europepmc   +1 more source

3P252 Is there sex difference in the hippocampus, the center of learning and memory? Part2(Neuroscience & Sensory systems,The 48th Annual Meeting of the Biophysical Society of Japan)

, 2010
Yasushi Hojo, Shimpei Higo, Masanao Uebayashi, Takeshi Yamazaki, Nobuhiro Harada, Seijiro Honma, Tetsuya Kimoto, Suguru Kawato   +7 more
openalex   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source