Results 131 to 140 of about 1,263,682 (340)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

The impact of sleep deprivation on the functional connectivity of auditory-related brain regions

Brain Research Bulletin
This study explored the effects of 36-hour acute sleep deprivation on the functional connectivity of auditory-related brain regions in healthy young males, examining its associations with alertness and emotional states.
Peng Zhang, Kai Wen, Huifeng Liu, Jing Wang, Qin Han, Fangfang Liu, Xiechuan Weng, Fan Xu   +7 more
doaj   +1 more source

Sensory system-specific associations between brain structure and balance. [PDF]

Neurobiol Aging, 2022
Hupfeld KE, McGregor HR, Hass CJ, Pasternak O, Seidler RD.   +4 more
europepmc   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

“Augmented Reality” in Martial: The Use and the Abuse of Olfactory and Gustatory Systems in Martial’s Epigrams

Humanitas
This paper examines Martial's innovative use of the senses of smell and taste in his epigrams, revealing how he transcends the limitations of the written word by inviting readers to interact with his work on a visceral level.
David Israel
doaj   +1 more source

An Optical Sensory System for Assessment of Residual Cancer Burden in Breast Cancer Patients Undergoing Neoadjuvant Chemotherapy. [PDF]

Sensors (Basel), 2023
Momtahen S, Momtahen M, Ramaseshan R, Golnaraghi F.   +3 more
europepmc   +1 more source

Sensory systems

Current Opinion in Neurobiology, 1992
Eric I. Knudsen, A.J. Hudspeth
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Analysis of the role of the QseBC two-component sensory system in epinephrine-induced motility and intracellular replication of Burkholderia pseudomallei. [PDF]

PLoS One, 2023
Meethai C, Vanaporn M, Intarak N, Lerdsittikul V, Withatanung P, Janesomboon S, Vattanaviboon P, Chareonsudjai S, Wilkinson T, Stevens MP, Stevens JM, Korbsrisate S.   +11 more
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source