Results 91 to 100 of about 204,143 (286)

Assessment of an Electronic Mechanical Sensory Threshold Testing Device (RatMet) in Wistar rats (Rattus norvegicus). [PDF]

J Am Assoc Lab Anim Sci, 2021
Schuster CJ, Pang DS.
europepmc   +1 more source

Multiple types of high-threshold calcium channels in rabbit sensory neurons: high-affinity block of neuronal L-type by nimodipine [PDF]

, 1992
RT McCarthy, PE TanPiengco
openalex   +1 more source

658 Injection site pain correlates with punctate pressure threshold measured by a sensory reduction device [PDF]

, 2023
E.M. Rao, J. Gallop, A.K. Maytin, J. Narang, N. Zevallos, C. Wilkowski, Y. Zhou, W. Summer, A. Chao, R.L. Klatzky, H. Choset, B. Carroll   +11 more
openalex   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

The impact of the gender on the pulp vitality testing for the various types of the conducting media: An original research

Journal of Pharmacy and Bioallied Sciences
Introduction: To identify gender-based differences in pulpal sensory thresholds in human teeth utilizing various conducting media. Materials and Methods: The study involved 50 participants of both genders equally distributed.
Vishwaja Uppalapati, Pradeep Onteru, Tony Mathew, Navjeet Singh Sandhu, Smita D Dutta, Jasasriya Nanda, Mohammed Mustafa   +6 more
doaj   +1 more source

Testing for sensory threshold in drinking water with added calcium: a first step towards developing a calcium fortified water. [PDF]

Gates Open Res, 2021
Cormick G, Matamoros N, Romero IB, Perez SM, White C, Watson DZ, Belizán JM, Sosa M, Gugole Ottaviano MF, Elizagoyen E, Garitta L.   +10 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

The effect of over-the-counter analgesics on changes to the sensory sensitivity of patients treated with transcutaneous electrical nerve stimulation

Scientific Reports
Analgesics and anti-inflammatory drugs represent the largest segment of over-the-counter (OTC) medicines. This observational study involved 247 patients treated for pain in outpatient physiotherapy. Using Transcutaneous Electrical Nerve Stimulation (TENS)
Joanna Witkoś, Magdalena Hartman-Petrycka, Grzegorz Błażejewski   +2 more
doaj   +1 more source

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

FEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source