Results 121 to 130 of about 92,239 (294)

Pain perception in autism. A study of sensory reactivity in children and adolescents with autism using quantitative sensory testing and psychophysiological correlates

open access: yesFrontiers in Neuroscience
BackgroundHyper- or hypo-reactivity to sensory input is a diagnostic criterion for autism spectrum disorder; however, it is still not fully characterized, despite its relevance to patients' quality of life.
Valentina Nicolardi   +4 more
doaj   +1 more source

Thermal and Vibratory Sensory Thresholds in Hemiplegic Patients Measured with Quantitative Sensory Test

open access: yes, 2009
뇌졸중으로 인한 편마비 환자에서는 운동마비 뿐만 아니라 체성감각인 촉각, 위치 감각, 온도감각, 또는 통각 등의 감각마비가 초래될 수 있다. 하지만 운동기능에 대한 평가와 달리, 감각기능의 평가는 상당히 주관적이고 재현성이 부족한 검사로 감각기능 상태를 정량화하기 어려워 환자의 상태 평가 및 추적관찰, 치료경과 판정 등에 어려움이 있어 왔다.
심은결
core  

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Improved Acuity and Dexterity but Unchanged Touch and Pain Thresholds following Repetitive Sensory Stimulation of the Fingers

open access: yesNeural Plasticity, 2012
Neuroplasticity underlies the brain’s ability to alter perception and behavior through training, practice, or simply exposure to sensory stimulation.
Rebecca Kowalewski   +3 more
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Estimated disributions of thermal and vibration sensory thresholds for healthy subjects

open access: yes, 1996
Objective. To estimate the distributions of thermal and vibration sensory thresholds in a healthy population taking into account important covariates.Methods.
Bartlett, Gillian
core  

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

open access: yesFEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Evaluation of sensory thresholds and perception of sodium chloride in grape juice and wine

open access: yes, 2014
Poor water quality and lack of rainfall can lead to higher salt loads in vineyard soil and the production of wine with sodium chloride (NaCl) concentrations that may affect wine quality or exceed regulatory limits.
Bastian, S.   +5 more
core   +1 more source

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

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