Results 41 to 50 of about 92,239 (294)

Comparison of Thresholds between Bipolar and Monopolar Electrical Cortical Stimulation

Neurologia Medico-Chirurgica, 2022
Electrical cortical stimulation is widely performed and is the gold standard for functional mapping in intractable epilepsy patients; however, a standard protocol has not yet been established.
Yasuhiro TAKAHASHI, Rei ENATSU, Aya KANNO, Seiichiro IMATAKA, Shoichi KOMURA, Tomoaki TAMADA, Kyoya SAKASHITA, Ryohei CHIBA, Takuro SAITO, Nobuhiro MIKUNI   +9 more
doaj   +1 more source

Visual distortion of body size modulates pain perception

, 2011
Pain is a complex subjective experience, that can be shaped by several cognitive, psychological and even contextual variables. For example, simply viewing the body reduces the reported intensity of acute physical pain.
Longo, Matthew R., Haggard, P, ,, Mancini, F, Mancini, F., Haggard, P., Marjolein P.M. Kammers, Flavia Mancini, Patrick Haggard, Kammers, MPM, Longo, MR, Matthew R. Longo, Kammers, M.P.M.   +12 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Validation of a Brazilian quantitative sensory testing (QST) device for the diagnosis of small fiber neuropathies

Arquivos de Neuro-Psiquiatria, 2011
Quantitative sensory testing (QST) is defined as the determination of thresholds for sensory perception under controlled stimulus. Our aim was to validate a new QST device for Brazilian sample. In 20 healthy adults, thermoalgesic thresholds were assessed
Pedro Schestatsky, Luciana Cadore Stefani, Paulo Roberto Sanches, Danton Pereira da Silva Júnior, Iraci Lucena Silva Torres, Letizzia Dall-Agnol, Luciane Fachin Balbinot, Wolnei Caumo   +7 more
doaj   +1 more source

Sensory Percepts Elicited by Chronic Macro-Sieve Electrode Stimulation of the Rat Sciatic Nerve

Frontiers in Neuroscience, 2021
Objective: Intuitive control of conventional prostheses is hampered by their inability to provide the real-time tactile and proprioceptive feedback of natural sensory pathways.
Nikhil S. Chandra, Weston M. McCarron, Ying Yan, Luis C. Ruiz, Eric G. Sallinger, Nathan K. Birenbaum, Harold Burton, Leonard Green, Daniel W. Moran, Wilson Z. Ray, Matthew R. MacEwan   +10 more
doaj   +1 more source

Tactile thresholds are preserved yet complex sensory function is impaired over the lumbar spine of chronic non-specific low back pain patients. A preliminary investigation

, 2010
Objectives: To investigate impairments in sensory function in chronic non-specific low back pain patients and the relationship between any impairment and the clinical features of the condition. Design: A cross-sectional case-control study.
George, PJ, Wand, Benedict M, Wand, BM, Di Pietro, Flavia, Neil E. O’Connell, George, Pamela, Di Pietro, FS, Benedict M. Wand, Flavia Di Pietro, O'Connell, NE, Pamela George, O\u27Connell, Neil E   +11 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Psychologic factors are related to some sensory pain thresholds but not nociceptive flexion reflex threshold in chronic whiplash

, 2008
Sensory hypersensitivity, central hyperexcitability [lowered nociceptive flexion reflex (NFR) thresholds], and psychologic distress are features of chronic whiplash. However, relationships between these substrates are not clear.
Pettiford, Catherine, Hodkinson, Emily, Sterling, M., Curatolo, Michele, Sterling, Michele, Souvlis, Tina   +5 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Mechanical and Thermal Sensory Testing in Normal Chondrodystrophoid Dogs and Dogs with Spinal Cord Injury caused by Thoracolumbar Intervertebral Disc Herniations

Journal of Veterinary Internal Medicine, 2016
Background Intervertebral disc herniation is a common cause of spinal cord injury (SCI) causing paralysis and sensory loss. Little quantitative information is available on the loss and recovery of sensation in dogs with SCI.
A.M. Gorney, S.R. Blau, C.S. Dohse, E.H. Griffith, K.D. Williams, J.‐H. Lim, D. Knazovicky, B.D.X. Lascelles, N.J. Olby   +8 more
doaj   +1 more source