Results 61 to 70 of about 92,239 (294)

A study of the sensory threshold

open access: yes, 1962
This thesis is concerned with the problem of defining the processes by which a subject selects a response to a stimulus. Initially certain topics in two areas of research, sensory scaling and threshold measurement, are revived. In relation to the first the conflict between Fechner's law, which is derived from threshold measurements, and the more recent
Treisman, M, Treisman, Michel
openaire   +2 more sources

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Sensory Irritation Potency of VOCs Measured Through Nasal Localization Thresholds [PDF]

open access: yes, 1996
In order to measure "odor unbiased" nasal pungency (e.g., sensory irritation) thresholds, we have resorted in the past to testing subjects with no olfaction (i.e., anosmics).
Cometto-Muniz, J. Enrique   +1 more
core  

Efficient estimation of sensory thresholds [PDF]

open access: yesBehavior Research Methods, Instruments, & Computers, 1986
Laboratory computers permit detection and discrimination thresholds to be measured rapidly, efficiently, and accurately. In this paper, the general natures of psychometric functions and of thresholds are reviewed, and various methods for estimating sensory thresholds are summarized.
openaire   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Study on the improvement of behavior and pain and the mechanism of Yangpafang in subacute Parkinson's disease model mice

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery
Objective Explore the therapeutic effect of Yangpafang on behavior and pain in subacute Parkinson's disease (PD) model mice and its possible mechanism. Methods Total 42 specific pathogen⁃free (SPF) C57BL/6J mice were randomly divided into control group ...
SHI Ying   +5 more
doaj   +1 more source

Investigating autonomic biomarkers of sensory processing patterns in young adults

open access: yes, 2022
Introduction: Autonomic nervous system functioning is theorised to underpin individual differences in sensory processing, with a small amount of supporting evidence.
Kerley, Lachlan   +2 more
core   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Exploring New and Modified Rejection-Type Thresholds Using Cricket Snack Crackers

open access: yes, 2020
Recently, sensory threshold concepts have been expanded to include affective perceptions of foods and beverages, especially measures of product rejection; however, each threshold interpretation depends largely on the methodology employed. By substituting
Marx, Brian   +7 more
core   +1 more source

Methodology for determination of two new sensory thresholds: Compromised acceptance threshold and rejection threshold

open access: yesFood Research International, 2015
The existing methodologies for determining thresholds generate unreliable estimates of the point at which the intensity of a stimulus begins to compromise acceptance or result in sensory rejection of a product. Thus, a new methodology was proposed for determination of two new sensory thresholds: the compromised acceptance threshold (CAT) and the ...
Tarcísio Lima Filho   +4 more
openaire   +3 more sources

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