Results 71 to 80 of about 84,211 (253)
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Journal of Acupuncture ResearchAlthough the spatial organization of the acupoints is a fundamental element in acupuncture practice, its physiological relevance has not been fully established.
You-Jeong Han +6 more
doaj +1 more source
Effects of acupuncture on sensory perception: a systematic review and meta-analysis.
PLoS ONE, 2014 BackgroundThe effect of acupuncture on sensory perception has never been systematically reviewed; although, studies on acupuncture mechanisms are frequently based on the idea that changes in sensory thresholds reflect its effect on the nervous system ...
Petra I Baeumler +5 more
doaj +1 more source
Evaluation of threshold limit methods for sensory data
Water Science and Technology, 2007 Current approaches to sensory thresholds, such as geometric means and logistic regression, ignore any formal consideration of uncertainty and variability. Various alternative methods based on approximate confidence and prediction intervals about the logistic regression were examined.
D, Gallagher, J, Cuppett
openaire +2 more sources
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source
Frontiers in NeurosciencePerception in natural environments requires integrating multisensory inputs while navigating our surroundings. During locomotion, sensory cues such as vision and audition change coherently, providing crucial environmental information.
Annalenia Malzacher +6 more
doaj +1 more source
Analysis of trigeminal nerve disorders after oral and maxillofacial intervention
Head & Face Medicine, 2010 Background Quantitative sensory testing (QST) is applied to evaluate somatosensory nerve fiber function in the spinal system. This study uses QST in patients with sensory dysfunctions after oral and maxillofacial surgery.
Ghassemi Alireza +8 more
doaj +1 more source
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
Measuring peripheral nerve involvement in Friedreich’s ataxia
Annals of Clinical and Translational Neurology, 2019 Objective Experimental therapies under development for Friedreich’s Ataxia (FRDA) require validated biomarkers. In‐vivo reflectance confocal microscopy (RCM) of skin is a noninvasive way to quantify Meissner’s corpuscle (MC) density and has emerged as a ...
Peter D. Creigh +6 more
doaj +1 more source
FEBS Open Bio, EarlyView.We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley +1 more source