Results 151 to 160 of about 141,733 (319)

Divergent Roles of mGlu2 and mGlu3 Receptors in Amyloid‐β Production and Cognitive Dysfunctions in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
This study explores the opposing effects of the mGluR2 and mGluR3 receptors on amyloid precursor protein processing. mGluR2 promotes amyloidogenic cleavage, while mGluR3 favors non‐amyloidogenic pathways. Using a brain‐penetrant nanobody as a mGluR2 positive allosteric modulator, the study uncovers how its chronic activation aggravates amyloid‐β burden
Pierre‐André Lafon   +21 more
wiley   +1 more source

Multi‐scale Optimization on Interfacial Evaporative Cooling for Photovoltaic Performance Enhancement

open access: yesAdvanced Science, EarlyView.
This study presents a passive siphon‐driven interfacial evaporative cooling technology for photovoltaics. A multiscale multiphysics model is developed and validated experimentally. Results show that optimizing installation parameters reduces operating temperature by up to 22.3 °C and boosts power efficiency by 8.9%, offering a practical pathway for ...
Fuxiang Li   +5 more
wiley   +1 more source

Faster and Durable: A Cell‐to‐System Validation of a Low‐Degradation Fast‐Charge Protocol for Li‐Ion Batteries

open access: yesAdvanced Science, EarlyView.
A physics‐based framework resolving graphite phase‐separation dynamics establishes a predictive, degradation‐aware fast‐charging methodology for commercial Li‐ion batteries. The resulting model‐informed protocol achieves 20%–80% state‐of‐charge in 14 min while matching the long‐term degradation of a commercial 25‐minute EV strategy.
Marco Lagnoni   +10 more
wiley   +1 more source

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