Results 141 to 150 of about 20,649 (261)

Dystrophia Smolandiensis is characterized by a novel NQO1 variant and a distinct phenotype from COL17A1‐associated epithelial recurrent erosion dystrophy

Acta Ophthalmologica, EarlyView.
Abstract Purpose To determine the molecular cause of the two epithelial recurrent erosion dystrophies, Dystrophia Smolandiensis and Dystrophia Helsinglandica, and to identify phenotypic differences between the two conditions. Methods DNA samples and clinical data from structured interview records were obtained from the Swedish families in which ...
Karl De Geer, Kristina Lagerstedt‐Robinson, Daniel Nilsson, Cilla Söderhäll, Björn Hammar, Erik Björck   +5 more
wiley   +1 more source

Integrating novel therapeutic strategies in myeloproliferative neoplasms: Driving disease‐directed progress

British Journal of Haematology, EarlyView.
Summary Over the past decade, there has been a substantial increase in the diversity and number of therapeutic options for myeloproliferative neoplasms (MPNs). While many remain within the clinical trial arena, the clinician and patient community have seen more approvals reaching the clinic and a rethink on how best we should be approaching these ...
Trung Q. Ngo, Maria Georgiou, Donal P. McLornan, Claire N. Harrison   +3 more
wiley   +1 more source

Attention and vigilance advantages related to formal musical training across childhood, adolescence and young adulthood

British Journal of Psychology, EarlyView.
Abstract Attention and vigilance are fundamental cognitive abilities that develop throughout childhood and adolescence and have been associated with cognitively demanding activities such as formal musical training. This cross‐sectional study examined whether individuals engaged in long‐term musical training show superior attention and vigilance ...
Rafael Román‐Caballero, Laura Trujillo, Paulina del Carmen Martín‐Sánchez, Elisa Martín‐Arévalo, Juan Lupiáñez   +4 more
wiley   +1 more source

Truncated drumlins and their implication for past sea level reconstructions

Boreas, EarlyView.
Coastal erosion of glacigenic sediments, particularly in the form of retreating drumlin bluffs, is a key process in paraglacial landscape evolution during periods of relative sea‐level (RSL) rise. As marine transgression reworks formerly subaerial glacial terrains, drumlins act as discrete sediment sources generating characteristic erosional and ...
Riccardo Arosio, Andrew Finlayson, Guillaume Michel, Dayton Dove   +3 more
wiley   +1 more source

A Review and Critique of Methods and Knowledge Gaps in Quantifying Spillover Effects from Protected Areas

Conservation Biology, EarlyView.
Abstract The sustainability of area‐based conservation initiatives depends on their value to society. Conservation often focuses inside protected areas, but the impacts of protected areas beyond their boundaries (spillovers) are critical for their social license.
Ilaria Gliottone, Teigan G. Collins, Ennis de Vos, Valeria Y. Mendez Angarita, Siwat Kongwarakom, Graeme S. Cumming   +5 more
wiley   +1 more source

SCD2 Alleviates Diabetes‐Associated Cognitive Dysfunction by Improving Microglial Lipid Metabolism

Cell Proliferation, EarlyView.
This study reveals a novel mechanism of microglial metabolic dysfunction in diabetic cognitive impairment. Defective SCD2 disrupts monounsaturated fatty acid (MUFA) metabolism, triggering mitochondrial oxidative phosphorylation dysfunction and leading to abnormal lipid droplet accumulation (marked by PLIN2).
Yang Yang, Juan He, Jing Zheng, Bing Shao, Lixin Shi, Miao Zhang   +5 more
wiley   +1 more source

Squamoid Eccrine Ductal Carcinoma: Case Series of a Rare, Potentially Aggressive Skin Cancer Associated With Immunosuppression

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Squamoid Eccrine Ductal Carcinoma (SEDC) is a rare cutaneous adenexal carcinoma first described in 1997. It has distinct biphasic features on histology which commonly result in misdiagnosis as Bowen disease or cutaneous squamous cell carcinomas (cSCC) if diagnostic skin biopsies are too superficial. This may lead to a delay in diagnosis. It is
Xiang Li Tan, Pooja Patel, Jeva Cernova, Sarah Hogan, Jason Thomson, Efthymios Hadjimichael, Sharanpal Jeetle, Dorota Markiewicz, Michael Sheaff, Nilukshi Wijesuriya, Mark Hawthorne, Graeme Moir, Matthew Stodell, Kapil Bhargava, Suchitra Chinthapalli, Catherine A. Harwood   +15 more
wiley   +1 more source

Sentinel Surveillance-Based Epidemiological Analysis of Foodborne Diseases in Shengsi County, China, 2019-2024 [Letter]. [PDF]

Infect Drug Resist
Zubaidah T.
europepmc   +1 more source

Diminishing returns of disease-modifying treatment in older participants of multiple sclerosis clinical trials. [PDF]

Mult Scler
Strijbis E, Mostert J, D'Haeseleer M, Moral E, Brieva Ruiz L, Comtois J, Killestein J, Repovic P, McPherson T, Cutter G, Koch M.   +10 more
europepmc   +1 more source

The Importance of the Larval Parasitoid Actia interrupta (Diptera: Tachinidae) in Low Density Eastern Spruce Budworm Populations

Entomologia Experimentalis et Applicata, EarlyView.
Actia interrupta is an important larval tachinid parasitoid during low‐density populations of the eastern spruce budworm. In the late 1980s during the outbreak collapse, Meteorus trachynotus was initially the most important species, but was replaced by A. interrupta. Host patch size and density had no impact on the parasitism rates by A.
Véronique Martel, Jacques Régnière, Jean‐Claude Thireau   +2 more
wiley   +1 more source