Results 161 to 170 of about 335,786 (287)
The FEBS Journal, EarlyView.Circadian disruption via constant light induces sex‐specific remodeling of the microbiome, lipid mediators, and immune responses. Females exhibit broader gut microbiota alterations, reduced jejunal oxylipins, increased hypothalamic N‐acylethanolamines, and a more inflammatory cytokine profile. Muscle responses are sex‐ and fiber type‐dependent: females
Pejman A. Pashaki +7 more
wiley +1 more source
The FEBS Journal, EarlyView.Lipid‐derived reactive electrophile molecules (REMs) are generated from fatty acids through lipoxygenase or cyclooxygenase‐assisted catalysis, or free radical‐induced lipid peroxidation events. REMs so‐produced covalently modify nearby protein‐cysteines, and in the case of ‘first responder’ proteins, can trigger gain‐of‐function signaling with context ...
Marcus J. C. Long +2 more
wiley +1 more source
Merkel cell carcinoma: an updated guide for pathologists
Histopathology, EarlyView.Merkel cell carcinoma (MCC) is an aggressive cutaneous neuroendocrine carcinoma for which the differential diagnosis can include other small cell malignancies (especially metastatic small cell carcinoma) or cutaneous carcinoma. Morphologic and immunophenotypic aberrancies in MCC can increase diagnostic challenge.
Paul W. Harms
wiley +1 more source
DETEKSI TUMPAHAN MINYAK MENGGUNAKAN METODE ADAPTIVE THRESHOLD PADA CITRA SATELIT SENTINEL-1A DI PERAIRAN UTARA KARAWANG [PDF]
The North Karawang Waters are one of the waters crossed by the Indonesian Archipelago Sea Lane (ALKI) where large ships and tankers cross this water area.
Tambunan, Efendy +2 more
core
Epigenetic and Metabolic Changes That Drive Trained Immunity in Response to Microbes and Vaccines
Immunology, EarlyView.This graphical abstract illustrates how microbial products, vaccines and microbial metabolites activate pattern‐recognition receptor signalling, inducing metabolic rewiring and epigenetic remodelling. These changes establish long‐lasting trained immunity through the functional reprogramming of haematopoietic progenitors and innate immune cells, thereby
Desalegn Abebaw +10 more
wiley +1 more source
, 2017 Keberadaan habitat hutan mangrove di kabupaten Cilacap sebagian besar berada di sekitar pantai Segara Anakan. Tumbuhan mangrove merupakan tumbuhan yang hidup di antara daratan dan lautan, memiliki fungsi ekologis di antaranya menjaga keseimbangan ...
Nanin Anggraini +4 more
core
Five‐year survival impact of adjuvant anti‐PD‐1 therapy in a nationwide cohort of stage III melanoma
Journal of the European Academy of Dermatology and Venereology, EarlyView.This nationwide real‐world cohort study was unable to demonstrate a population‐level survival benefit of adjuvant anti‐PD‐1 in stage III melanoma. Matched analyses suggested higher OS in treated patients. However, limited statistical power and potential residual confounding preclude firm conclusions.
Marie B. Weitemeyer +11 more
wiley +1 more source
Silicon Formalism: Rules, Standards, and Judge AI
Journal of Empirical Legal Studies, EarlyView.ABSTRACT This paper replicates a judicial experiment originally conducted on 61 U.S. federal judges, this time with GPT‐5 as the decision‐maker. The experiment involves a choice‐of‐law dispute in a hypothetical automobile accident case, where three variables are manipulated: (1) whether the applicable doctrine is a rule or a standard, (2) whether the ...
Eric A. Posner, Shivam Saran
wiley +1 more source
Olaparib‐associated cutaneous vasculitis in a patient with breast cancer
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Marcial Álvarez‐Salafranca +3 more
wiley +1 more source