Results 161 to 170 of about 25,781 (306)

Attention and vigilance advantages related to formal musical training across childhood, adolescence and young adulthood

open access: yesBritish Journal of Psychology, EarlyView.
Abstract Attention and vigilance are fundamental cognitive abilities that develop throughout childhood and adolescence and have been associated with cognitively demanding activities such as formal musical training. This cross‐sectional study examined whether individuals engaged in long‐term musical training show superior attention and vigilance ...
Rafael Román‐Caballero   +4 more
wiley   +1 more source

Safety, tolerability, pharmacokinetics and pharmacodynamics of the spleen tyrosine kinase inhibitor BI 894416 in healthy volunteers and patients with asthma

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Spleen tyrosine kinase (SYK) has broad biological functions in inflammation and immunity. The orally administered SYK inhibitor BI 894416 was investigated in a single‐rising‐dose Phase I study in healthy volunteers and in a combined single‐ and multiple‐rising‐dose Phase Ib study in patients with mild asthma ...
Saskia Carstensen‐Aurèche   +8 more
wiley   +1 more source

Analysis of the 2019 Midwest US Flooding Using NASA Data [PDF]

open access: yes
In the wake of Winter Storm Ulmer, an intense "bomb cyclone" that set preliminary low-pressure records, historic flooding occurred in 41 locations across the Midwest United States, causing many streams and rivers - including the Platte, Missouri, and ...
Bagwell, Ross, Peters, Byron
core   +1 more source

Glucose Metabolism Regulating Colorectal Cancer Initiation and Progression

open access: yesCancer Science, EarlyView.
Drugs and compounds targeting glycolysis in CRC and the mechanisms by which these drugs inhibit their respective targets. ABSTRACT Colorectal cancer (CRC) is one of the most common types of invasive cancer worldwide, which has the characteristics of poor curative effect and poor prognosis. Increasing evidence suggests that hyperactivated glucose uptake
Meiyi Lin, Junpeng Cui
wiley   +1 more source

SCD2 Alleviates Diabetes‐Associated Cognitive Dysfunction by Improving Microglial Lipid Metabolism

open access: yesCell Proliferation, EarlyView.
This study reveals a novel mechanism of microglial metabolic dysfunction in diabetic cognitive impairment. Defective SCD2 disrupts monounsaturated fatty acid (MUFA) metabolism, triggering mitochondrial oxidative phosphorylation dysfunction and leading to abnormal lipid droplet accumulation (marked by PLIN2).
Yang Yang   +5 more
wiley   +1 more source

Afforestation of tropical savannas has mixed consequences for bird communities

open access: yesConservation Science and Practice, EarlyView.
Moving beyond the prevailing binary perception of savanna afforestation being either ‘good’ or ‘bad’ for native biodiversity, our data suggests that plantations on the rainfall extremes should be viewed as important supplementary habitats for biodiversity.
Siddhant Mhetre   +5 more
wiley   +1 more source

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