Microglial Transmembrane 119 (Tmem119) is Protective in Ischemic Stroke
Microglial Tmem119 knockdown increases inflammatory signaling following oxygen–glucose deprivation (OGD). Tmem119 overexpression attenuates IRAK4‐mediated inflammation, enhances IL‐10 production, reduces ischemic brain injury, and improves neurological outcomes after stroke.
Afzal Misrani +6 more
wiley +1 more source
Function-Decoupled Environment-Gated Multimodal Fusion for Chlorophyll-<i>a</i> Retrieval in a Cold-Arid Shallow Lake. [PDF]
Li H, Li H, Fu X, Shi X.
europepmc +1 more source
ABSTRACT Tropical oyster reefs are ecologically important ecosystems that support significant ecosystem services across coastal seascapes. Yet their current distribution and conservation needs remain poorly understood, limiting the effectiveness of management.
Marina A. Richardson +8 more
wiley +1 more source
Contralateral Axillary Lymph Node Metastases Detected by Repeat Sentinel Lymph Node Biopsy in a Patient with Ipsilateral Breast Tumor Recurrence: A Case Report. [PDF]
Uchida N, Suda T.
europepmc +1 more source
Spatially Resolved Metabolomics of Optimal Cutting Temperature (OCT) Compound‐Embedded Tumors
ABSTRACT Mass spectrometry imaging (MSI) is emerging as a powerful tool for uncovering the distribution of metabolites in the tumor microenvironment and studying tumor metabolism in vivo. To date, MSI of biobanked tissues contextualized by patient data has been limited to peptides, proteins, and glycans—with few examples for metabolites.
Joseph Monaghan +6 more
wiley +1 more source
On predictability of slip, rupture geometry, and speed of the 2025 M7.8 Mandalay, Myanmar, earthquake. [PDF]
Ulrich T +11 more
europepmc +1 more source
ABSTRACT Mutant p53 accumulation may complement conformation‐sensitive RHSVV recognition, but the required exposure discrimination depends on tumor coverage and normal‐cell stress. We analyzed 809 tumors and 523 adjacent‐normal specimens from eight CPTAC cohorts.
Takehiro Ishikawa
wiley +1 more source
Genomic Surveillance and Phylogenetic Analysis of Influenza A(H1N1) pdm09 and A(H3N2) Viruses in Burkina Faso, 2024. [PDF]
Sawadogo C +13 more
europepmc +1 more source
This study presents the first application of a dual‐band satellite thermal monitoring technique in New Zealand and Tonga, using the 2019 eruption of Whakaari/White Island and the persistently active Lofia crater on Tofua volcano as case studies. At Whakaari/White Island, near‐synchronous Landsat‐8 and Sentinel‐2A data (16 min interval) were analysed ...
Salman Ashraf +3 more
wiley +1 more source
Synergistic Regulation of Biomaterials and Macrophages: A Novel Paradigm in Immunotherapy
Bioengineered materials mediating the modulation of macrophage plasticity and inflammatory signals in the tumor microenvironment effectively remodel immunoregulatory states, boost antitumor immunity, and promote tissue repair, achieving synergistic therapeutic outcomes.
Jiayu Zhang +16 more
wiley +1 more source

