Results 181 to 190 of about 25,781 (306)

Molecular Signatures of Peripheral and Central Dental Pulp Subpopulations in Response to Streptococcus mutans: A Bulk RNA‐Seq Analysis

International Endodontic Journal, EarlyView.
ABSTRACT Aim The dental pulp is an immunologically active tissue that responds dynamically to cariogenic challenge. Peripheral pulp cells adjacent to dentine encounter bacterial stimuli earlier than cells located in the central pulp. To investigate signalling and immune interactions, this study profiled the transcriptomes of dentine‐adherent cells ...
Sandra Pohl, Maximilian L. Huber, Tobias Akamp, Andreas Rosendahl, Melanie Linnebank, Lea Schreiber, Claudia Gebhard, Nicholas Strieder, Michael Rehli, Wolfgang Buchalla, Matthias Widbiller   +10 more
wiley   +1 more source

Genetic Determinants of Peanut‐Specific IgG4 Levels in the Context of Sustained Oral Peanut Exposure in the LEAP Study

Immunology, EarlyView.
A cumulative genetic score based on IgG4‐associated variants explains a substantial proportion of variance in psIgG4 levels during sustained peanut consumption, highlighting strong gene‐by‐environment interactions. Our findings suggest that early, sustained peanut consumption, in combination with genetic factors, promotes a protective immune response ...
Kanika Kanchan, Karen Cerosaletti, James A. Perry, George DuToit, Monali Manohar, Hua Ling, Justin E. Paschall, Srinath Sanda, R. Sharon Chinthrajah, Gerald T. Nepom, Kari C. Nadeau, Stacie M. Jones, Gideon Lack, Ingo Ruczinski, Rasika A. Mathias   +14 more
wiley   +1 more source

Projected Climate‐Suitable Area for Apis mellifera (Apidae) and Its Spatial Overlap With a Mining Tailings Footprint in South‐East Brazil

Journal of Applied Entomology, EarlyView.
ABSTRACT Climate change and environmental disasters can jointly impact species distributions and ecosystem stability, including pollinators and the resources they rely on. We used occurrence and climate data to predict the distribution of Apis mellifera in the Doce River Basin, south‐east Brazil, under baseline and future scenarios (2050).
Flávio Mariano Machado Mota, Débora Lima‐Santos, Walisson Kenedy‐Siqueira, Kamilla Ingred Castelan Vieira, Geraldo Wilson Fernandes   +4 more
wiley   +1 more source

A leucine‐rich‐repeat receptor‐like kinase SERL1 phosphorylates and stabilizes OsALDH2B1 to promote alkaline tolerance and grain size in rice

Journal of Integrative Plant Biology, EarlyView.
The rice aldehyde dehydrogenase OsALDH2B1 enhances grain size and tolerance to alkaline soil by repressing GRAIN SIZE 3 and activating catalases. SERL1‐mediated phosphorylation stabilizes OsALDH2B1 under stress, establishing a signaling axis that overcomes growth‐defense trade‐offs and provides a direct target for breeding high‐yield, alkaline ...
Zemin Ma, Xuanlin Gao, Shuaizu An, Mengyuan Chen, Biaoming Zhang, Lei Zhou, Shengyuan Sun, Ming Li, Feng Yu, Shiyou Lü, Zhaohui Chu, Aiqing You, Yinggen Ke, Pingfang Yang   +13 more
wiley   +1 more source

Diminishing returns of disease-modifying treatment in older participants of multiple sclerosis clinical trials. [PDF]

Mult Scler
Strijbis E, Mostert J, D'Haeseleer M, Moral E, Brieva Ruiz L, Comtois J, Killestein J, Repovic P, McPherson T, Cutter G, Koch M.   +10 more
europepmc   +1 more source

Hoffmann's two‐toed sloth II: Muscle architectural properties in the thoracic limb of Choloepus (Pilosa: Xenarthra)

Journal of Anatomy, EarlyView.
Two‐toed sloths use their thoracic limbs for more frequent and greater suspensory support than three‐toed sloths and have muscle architectural properties consistent with stability of the pectoral girdle, enhanced flexor force/torque applied at the shoulder and elbow joints, and grip on the support as indicated by their myology. Abstract Two‐toed sloths
C. S. Tucker, A. M. Mossor, K. B. Spainhower, J. A. Avey‐Arroyo, M. T. Butcher   +4 more
wiley   +1 more source

Hoffmann's two‐toed sloth I: Complete myology in the thoracic limb of Choloepus (Pilosa: Xenarthra)

Journal of Anatomy, EarlyView.
Two‐toed sloths use their thoracic limbs for more frequent and prolonged suspensory support than three‐toed sloths and accordingly demonstrate myological traits consistent with stability of the pectoral girdle, enhanced flexor force/torque applied at the elbow joint, and grip on the support.
C. S. Tucker, A. M. Mossor, J. A. Avey‐Arroyo, M. T. Butcher   +3 more
wiley   +1 more source

Spatiotemporal prediction of mining-induced surface subsidence using integrated D-InSAR and boltzmann time function models. [PDF]

PLoS One
Zhou W, Zou Y, Chai H, Ma M, Cai L, Hu J.   +5 more
europepmc   +1 more source

Inflammatory and Immunological Basis of Periodontal Diseases

Journal of Periodontal Research, EarlyView.
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima, Marion Arce, Mario Romandini, Thomas Van Dyke   +3 more
wiley   +1 more source

Enhanced Landslide Monitoring in Complex Mountain Terrain Using Distributed Scatterer InSAR and Phase Optimization: A Case Study in Zhenxiong, China. [PDF]

Sensors (Basel)
Liang J, Tang B, Li M, Cai F, Wei L, Huang C.   +5 more
europepmc   +1 more source