Noradrenergic inhibition of definitive POMC neurons through direct and indirect mechanisms
Norepinephrine and the α2‐adrenoceptor agonist UK 14,304 robustly inhibit definitive arcuate POMC neurons. Direct inhibition is mediated by ADRA2A‐dependent activation of potassium conductances, while additional indirect mechanisms also contribute. In vivo, inducible POMC‐specific Adra2a deletion minimally affects energy balance and modestly impairs ...
Olivier Lavoie +6 more
wiley +1 more source
Soil total nitrogen prediction based on multi-temporal synthetic Sentinel-2 images under different land use types. [PDF]
Ouyang YL, Wu W, Liu HB.
europepmc +1 more source
Remote Sensing of Endogenous Pigmentation by Inducible Synthetic Circuits in Grasses
ABSTRACT Plant synthetic biology holds great promise for engineering plants to meet future demands. Genetic circuits are being designed, built and tested in plants to demonstrate the proof of concept. However, developing these components in monocots, which the world relies on for grain, lags behind dicot models, such as Arabidopsis thaliana and ...
Dong‐Yeon Lee +13 more
wiley +1 more source
Three-dimensional surface deformation field monitoring and influencing factors analysis in mountainous areas based on SBAS-INSAR technology (Tianjin, China). [PDF]
Shang J +5 more
europepmc +1 more source
CDAHFD‐induced hepatic steatosis stimulates CBP/β‐catenin signaling in hepatocytes, leading to increased production of the downstream effector MMP‐7. Hepatocyte‐derived MMP‐7 contributes to fibrogenic responses and is associated with the progression of liver fibrosis.
Jun Imamura +5 more
wiley +1 more source
Mature fault mechanics revealed by the highly efficient 2025 Mandalay earthquake. [PDF]
Lindsey EO +4 more
europepmc +1 more source
ABSTRACT Rationale The Delta Ray Isotope Ratio Infrared Spectrometer enables to determine δ13C and δ18O values of CO2. The measurements are calibrated against internal reference gas standards. For discrete carbonate or dissolved inorganic carbon (DIC) samples, the manufacturer recommends a calibration against two isotopically different carbonate ...
Maximilian Hansen +3 more
wiley +1 more source
Invasive apocrine carcinoma of the breast-a surgeon's perspective on diagnosis, pitfalls, and evolving management options. [PDF]
Jaka RC, Swaminathan AM, Shetty SK.
europepmc +1 more source
Abstract Mesoscale eddies play a key role in transporting heat poleward across the Antarctic Circumpolar Current (ACC). In addition to conventional eddies (warm‐core anticyclones and cold‐core cyclones), recent studies have detected a significant number of unconventional eddies at the surface (cold‐core anticyclones and warm‐core cyclones).
Shimin Yuan, Ruiyi Chen, Yiyong Luo
wiley +1 more source
High-resolution maps of rice cropping intensity across Southeast Asia. [PDF]
Ginting FI +10 more
europepmc +1 more source

