Results 91 to 100 of about 150,886 (327)
Advanced Science, EarlyView.Seasonal cold adaptation is vital for insect survival, yet the molecular mechanisms linking diapause to mitochondrial resilience remain largely unresolved. We identify ascaroside C9 (asc‐C9) as a key endocrine signal that enhances diapause survival during cold stress by activating the AKHR–PGC1α–UCP4 axis, thereby driving cold‐induced lipolysis and ...
Jiao Zhou +14 more
wiley +1 more source
Crowdsourcing EO datasets to improve cloud detection algorithms and land cover change [PDF]
, 2017 Involving citizens in science is gaining considerable traction of late. With positive examples (e.g. Geo-Wiki, FotoQuest Austria), a number of projects are exploring the options to engage the public in contributing to scientific research, often by ...
Aleksandrov, M. +6 more
core
XIAP Stabilizes DDRGK1 to Promote ER‐Phagy and Protects Against Noise‐Induced Hearing Loss
Advanced Science, EarlyView.Mechanism of GAS‐mediated protection against noise‐induced hearing loss (NIHL). Noise exposure activates the ATF4/eIF2α axis, downregulating XIAP and promoting DDRGK1 degradation, thereby inhibiting ER‐phagy and leading to hair cell (HC) death. GAS treatment rescues XIAP and DDRGK1 expression, reactivating ER‐phagy to mitigate HC loss, synaptic damage,
Lin Yan +13 more
wiley +1 more source
Sentinel-2 Pan Sharpening—Comparative Analysis [PDF]
The 2nd International Electronic Conference on Remote Sensing, 2018 Pan Sharpening is an important part of the Remote Sensing science. Obtaining high spatial resolution data can be crucial in some studies. Sentinel-2 provides data of 10, 20 and 60 m, and it is a promising program for Earth observation studies. Although Sentinel-2 provides a high range of multispectral bands, the lack of panchromatic band disables the ...
openaire +1 more source
Identifying cropped areas in small growers agricultural regions using data mining for food security [PDF]
, 2014 The present study aimed at testing the potential of the future mission SENTINEL-2 (European Copernicus program) to map croplands in a region of Madagascar characterized by small size fields and frequent cloud covering.
Andriandrahona Fidiniaina, Ramahandry +6 more
core
Advanced Science, EarlyView.Mature red blood cells (RBCs) can capture extracellular DNA, with short fragments homologous to cfDNA. This uptake is mediated by apoptotic bodies, which induce RBC oxidative stress, deformation, and accelerated in vivo clearance. The rbcDNA abundance correlates with tumor burden and therapeutic response, highlighting its potential as a liquid biopsy ...
Zihang Zeng +20 more
wiley +1 more source
Haze compensation and atmospheric correction for Sentinel-2 data [PDF]
, 2016 Sentinel-2 data bring the opportunity to analyze landcover at a high spatial accuracy together with a wide swath. Nevertheless, the high data volume requires a per granule analysis.
Makarau, Aliaksei +3 more
core
Advanced Science, EarlyView.IGF‐1 deficiency underlies poor ovarian response (POR), as reduced levels in follicular fluid and granulosa cells impair antral follicle formation and compromise reproductive outcomes. Including IGF‐1 as a biomarker significantly enhances the accuracy of models predicting both PORrisk and pregnancy success.
Zhu Hu +9 more
wiley +1 more source
Advanced Science, EarlyView.This study shows that integrin receptor CD49a (Itga1 gene) is significantly upregulated in hyperactivated microglia and microglia‐specific knockdown of Itga1 rescues neuroinflammation and neurodegeneration in a chronic Parkinson's disease (PD) model by targeting PGAM5‐mediated mitochondrial dysfunction and NLRP3 activation. Targeted inhibition of CD49a
Huanpeng Lu +6 more
wiley +1 more source
Development of a prediction model based on LASSO regression to evaluate the risk of non-sentinel lymph node metastasis in Chinese breast cancer patients with 1–2 positive sentinel lymph nodes [PDF]
, 2021 Lei Meng +6 more
openalex +1 more source