Results 71 to 80 of about 149,547 (281)

The Detection of Wetlands And Wetland Fragmentation Using Sentinel 1 And 2 Imagery: The Example of Southern Nigeria [PDF]

open access: gold, 2021
Sani Idris Garba   +4 more
openalex   +1 more source

Allosteric Modulation of Pathological Ataxin‐3 Aggregation: A Path to Spinocerebellar Ataxia Type‐3 Therapies

open access: yesAdvanced Science, EarlyView.
This study uncovers a new allosteric site in the Josephin domain of ataxin‐3 targeted by the molecular tweezer CLR01, which modulates protein aggregation, improves synaptic function in neuronal cells, and delays motor dysfunction in animal models.
Alexandra Silva   +28 more
wiley   +1 more source

Improving Accuracy Estimation of Forest Aboveground Biomass Based on Incorporation of ALOS-2 PALSAR-2 and Sentinel-2A Imagery and Machine Learning: A Case Study of the Hyrcanian Forest Area (Iran)

open access: yesRemote Sensing, 2018
The main objective of this research is to investigate the potential combination of Sentinel-2A and ALOS-2 PALSAR-2 (Advanced Land Observing Satellite -2 Phased Array type L-band Synthetic Aperture Radar-2) imagery for improving the accuracy of the ...
Sasan Vafaei   +6 more
doaj   +1 more source

Performance of Sentinel-2 NDVI for assessing the relationship between vegetation and soil moisture under extreme drought conditions [PDF]

open access: yes, 2012
Initial indications are that the enhanced spatial and spectral resolution of Sentinel-2 would allow for better assess- ment of vegetation condition, and consequently improved application in conditions of moisture deficit/drought.
West, H.   +3 more
core  

A Cold Stress‐Activated Endocrine Sentinel Chemical Hormone Promotes Insect Survival via Mitochondrial Adaptations Through the Adipokinetic Hormone Receptor

open access: yesAdvanced Science, EarlyView.
Seasonal cold adaptation is vital for insect survival, yet the molecular mechanisms linking diapause to mitochondrial resilience remain largely unresolved. We identify ascaroside C9 (asc‐C9) as a key endocrine signal that enhances diapause survival during cold stress by activating the AKHR–PGC1α–UCP4 axis, thereby driving cold‐induced lipolysis and ...
Jiao Zhou   +14 more
wiley   +1 more source

Red Blood Cells Internalize Extracellular DNA via Apoptotic Bodies with Clinical Relevance to Cancer Patients

open access: yesAdvanced Science, EarlyView.
Mature red blood cells (RBCs) can capture extracellular DNA, with short fragments homologous to cfDNA. This uptake is mediated by apoptotic bodies, which induce RBC oxidative stress, deformation, and accelerated in vivo clearance. The rbcDNA abundance correlates with tumor burden and therapeutic response, highlighting its potential as a liquid biopsy ...
Zihang Zeng   +20 more
wiley   +1 more source

Satellite remote sensing reveals a positive impact of living oyster reefs on microalgal biofilm development [PDF]

open access: yes, 2018
Satellite remote sensing (RS) is routinely used for the large-scale monitoring of microphytobenthos (MPB) biomass in intertidal mudflats and has greatly improved our knowledge of MPB spatio-temporal variability and its potential drivers.
B. Cognie   +9 more
core   +5 more sources

CD27 and ICOS as Targets of PD‐1/PD‐L1 Signaling to Regulate Resident Memory CD8+ T‐Cell‐Mediated Pulmonary Protection and Pathology

open access: yesAdvanced Science, EarlyView.
Here it is revealed that the costimulatory receptors CD27 and ICOS are essential for the long‐term maintenance of PD‐1high CD8+ TRM cells following influenza infection. PD‐L1 blockade enhances the proliferation and activation of these cells through Nur77 activation downstream of the CD27/ICOS signaling axis, thereby boosting host immunity against ...
Yuanyuan Chen   +16 more
wiley   +1 more source

Identifying cropped areas in small growers agricultural regions using data mining for food security [PDF]

open access: yes, 2014
The present study aimed at testing the potential of the future mission SENTINEL-2 (European Copernicus program) to map croplands in a region of Madagascar characterized by small size fields and frequent cloud covering.
Andriandrahona Fidiniaina, Ramahandry   +6 more
core  

CD169+ Macrophage‐Targeted Immunomodulator to Restore Phagocytic Function and Enhance Antigen Presentation for Lymphatic Metastasis Eradication

open access: yesAdvanced Science, EarlyView.
A CD169+ macrophage‐targeted immunomodulator (G‐LNP@S‐D) is developed to co‐deliver a SHP2 inhibitor and STING agonist, thereby restoring phagocytic function, enhancing antigen presentation by CD169+ macrophages, and promoting T cell priming to eradicate lymphatic metastasis.
Xiayun Chen   +9 more
wiley   +1 more source

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