Results 21 to 30 of about 41,652 (228)

Current status, trends, and controversies in the selection of gastrectomy procedures: Insights from two nationwide questionnaire surveys conducted over a 7‐year interval in Japan

Annals of Gastroenterological Surgery, EarlyView.
This study investigates the evolving trends and challenges in gastrectomy procedures in Japan, drawing on two nationwide surveys conducted in 2014 and 2021. Results show a significant shift toward minimally invasive and function‐preserving surgeries, such as laparoscopic and robot‐assisted gastrectomy, with an emphasis on enhancing postoperative ...
Koji Nakada, Hideyuki Kashiwagi, Shinichi Kinami, Hiroharu Yamashita, Nobuyoshi Hanyu, Atsushi Oshio, Michio Kaminishi, Yasuyuki Seto   +7 more
wiley   +1 more source

Essential Updates 2023/2024: Recent Advances of Multimodal Approach in Patients for Gastric Cancer

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Gastric cancer remains a major global health burden, especially in East Asia. Recent years have brought significant advances in multimodal management, including surgery, perioperative chemotherapy, immunotherapy, and supportive care. This review summarizes key updates from 2023 to 2024, focusing on surgical innovations, perioperative systemic ...
Katsutoshi Shoda, Yoshihiko Kawaguchi, Suguru Maruyama, Daisuke Ichikawa   +3 more
wiley   +1 more source

Fluorescence Guided Surgery in Gastric Cancer: What Do We Have and What Can We Do?

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background and Objective Fluorescence imaging has emerged as a valuable adjunct in gastric surgery, enhancing resection precision and oncologic outcomes. However, the use of indocyanine green (ICG) remains controversial due to uncertainties in efficacy and administration. A lack of standardized protocols persists.
Chun Zhuang, Han‐Kwang Yang
wiley   +1 more source

Harnessing the Biological Responses Induced by Nanomaterials for Enhanced Cancer Therapy

Aggregate, EarlyView.
Nanomaterial (NM)‐induced toxicity can be strategically repurposed for cancer therapy. This review summarizes the mechanism by which NMs selectively activate specific cellular processes to regulate cell fate independently. We also discussed how NMs‐induced biological responses can be leveraged as therapeutic strategies for cancer treatment.
Liting Wang, Hao Fu, Jiangtao Lin, Meng Zhao, Chuanrong Chen, Hongze Liao, Yourong Duan   +6 more
wiley   +1 more source

Illuminating the Unseen and Targeting the Untreatable: Aggregation‐Induced Emission Nanoparticles as Intelligent, Immune‐Compatible Tools for Precision Cancer Theranostics

Aggregate, EarlyView.
Rationally engineered AIE nanoparticles can unite deep‐tissue imaging, photodynamic therapy, photothermal therapy, and immune microenvironment reprogramming. Through precise photophysical tuning and targeted delivery, these intelligent nanoplatforms enable real‐time monitoring, potent tumor eradication, and immune activation, offering a versatile and ...
Quazi T. H. Shubhra, Robert Musiol, Huachun Pan, Qiang Cai, Xiaosong He, Xiaojun Cai   +5 more
wiley   +1 more source

Intranasal Wharton's Jelly‐Derived Mesenchymal Stem Cell Therapy, Alone or in Conjunction With Therapeutic Hypothermia, Alleviates Neonatal Hypoxic‐Ischemic Brain Injury in Mice

Annals of Neurology, EarlyView.
This study demonstrates that intranasal Wharton's jelly‐derived mesenchymal stem cell (WJ‐MSC) administration at 3 or 10 days post‐insult reduced the lesion size and sensorimotor impairment following neonatal hypoxic‐ischemic (HI) brain injury in mice. WJ‐MSCs expressed receptors for HI‐upregulated chemokines and migrated from the nasal cavity into the
Caroline G. M. de Theije, Sara T. De Palma, Josine E. G. Vaes, Katiuscia Dallaglio, Giorgia Volpi, Diego Ardigò, Sabine van Rijt, Frank van Bel, Manon J. N. L. Benders, Cora H. A. Nijboer   +9 more
wiley   +1 more source

The Role of Machine Learning to Detect Occult Neck Lymph Node Metastases in Early‐Stage (T1‐T2/N0) Oral Cavity Carcinomas

Head &Neck, EarlyView.
ABSTRACT Objective Oral cavity carcinomas (OCCs) represent roughly 50% of all head and neck cancers. The risk of occult neck metastases for early‐stage OCCs ranges from 15% to 35%, hence the need to develop tools that can support the diagnosis of detecting these neck metastases.
Stefania Troise, Lorenzo Ugga, Maria Esposito, Maria Positano, Andrea Elefante, Serena Capasso, Renato Cuocolo, Raffaele Merola, Umberto Committeri, Vincenzo Abbate, Paola Bonavolontà, Riccardo Nocini, Giovanni Dell’Aversana Orabona   +12 more
wiley   +1 more source

Neck Dissection Reduces Risk of Recurrence in Early‐Stage Oral Tongue Cancer

Head &Neck, EarlyView.
ABSTRACT Background Patterns of failure in early‐stage oral tongue squamous cell carcinoma (OTSCC) managed with surgery alone remain understudied. Methods Retrospective cohort study from 2000 to 2022 at a single tertiary care center evaluated pT1‐T2N0 OTSCC patients who underwent partial glossectomy with or without elective neck dissection (END ...
Jaclyn Lee, Tan Ding, Mae Wimbiscus, Dandan Liu, Melanie D. Hicks, Alexander J. Langerman, Robert J. Sinard, Kyle Mannion, Sarah L. Rohde, Eben L. Rosenthal, Michael C. Topf   +10 more
wiley   +1 more source

Twenty‐year survival outcomes after multipeptide vaccination for resected high‐risk melanoma: A post‐hoc analysis of a randomized clinical trial

International Journal of Cancer, EarlyView.
What's New? While melanoma vaccines have shown therapeutic promise, predicting their clinical benefits is challenged by factors such as delayed response to immunotherapy and scarcity of biomarkers. Here, the authors examined the long‐term efficacy of vaccination with either 4 or 12 class I MHC‐restricted peptides in high‐risk melanoma.
Emily K. Ninmer, Hong Zhu, Kimberly A. Chianese‐Bullock, Craig L. Slingluff Jr.   +3 more
wiley   +1 more source

Exploring the potential of AI‐powered applications for clinical decision‐making in gynecologic oncology

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective The rise of artificial intelligence (AI) and large language models like Llama, Gemini, or Generative Pretraining Transformer (GPT) signals a promising new era in natural language processing and has significant potential for application in medical care.
Bastian Meyer, Raphael Kfuri‐Rubens, Georg Schmidt, Maliha Tariq, Caroline Riedel, Florian Recker, Fabian Riedel, Marion Kiechle, Maximilian Riedel   +8 more
wiley   +1 more source