The incidence of desmoplastic melanoma (DM) in Sweden remains stable, unlike rising cutaneous melanoma rates. Despite advanced tumour features, DM patients have better survival outcomes. However, recent survival improvements are lacking, potentially due to limited treatment options compared to other melanoma subtypes.
Yodit Girmay+5 more
wiley +1 more source
66 patients from 22 centers received adjuvant treatment after relapse under or after previous adjuvant therapy with BRAF + MEK or PD‐1. Data highlight a significant benefit when switching from PD‐1 to BRAF + MEK adjuvant therapy compared to a switch from BRAF + MEK to PD‐1 adjuvant regimens.
Katharina Schumann+25 more
wiley +1 more source
Comparison of targeted axillary dissection with sentinel node biopsy alone on nodal recurrence for patients who have node-positive breast cancer treated with neoadjuvant chemotherapy: a critical appraisal. [PDF]
Venkataraman J, Al-Shamari A, Mokbel K.
europepmc +1 more source
What Is a False Negative Sentinel Node Biopsy: Definition, Reasons and Ways to Minimize It?
K. Kataria+2 more
semanticscholar +1 more source
Non‐invasive characterization of melanoma depth at single‐cell resolution
Non‐invasive determination of Breslow depth would be beneficial for the clinical management of melanoma. We demonstrate that RSOM can achieve non‐invasive imaging of single melanocytes up to several millimetres in tissue. A pilot clinical study showed a high degree of correlation between RSOM and the standard for Breslow depth determination.
Juan Aguirre+11 more
wiley +1 more source
Sentinel Node Mapping with Blue Dye Injection after Lumpectomy Specimen Removal: Implications for Fluorescence-Guided Breast Surgery. [PDF]
Cruz HSS+6 more
europepmc +1 more source
A deep learning–clinical nomogram hybrid for predicting sentinel lymph node metastasis in melanoma
We developed MISSLE, a deep learning–clinical nomogram hybrid model, to predict sentinel lymph node metastasis in invasive cutaneous melanoma with a high area under the receiver operating characteristic curve of 0.950 on the test set. MISSLE identifies key histopathological features and integrates AI for improved clinical decision‐making.
Minh‐Khang Le+8 more
wiley +1 more source
Comparison of Targeted Axillary Dissection with Sentinel Node Biopsy Alone on Nodal Recurrence for Patients who have Node-Positive Breast Cancer Treated with Neoadjuvant Chemotherapy. [PDF]
Boyle MK+4 more
europepmc +1 more source