Results 31 to 40 of about 55,964 (304)

Targeting Microglial CD49a Inhibits Neuroinflammation and Demonstrates Therapeutic Potential for Parkinson's Disease

Advanced Science, EarlyView.
This study shows that integrin receptor CD49a (Itga1 gene) is significantly upregulated in hyperactivated microglia and microglia‐specific knockdown of Itga1 rescues neuroinflammation and neurodegeneration in a chronic Parkinson's disease (PD) model by targeting PGAM5‐mediated mitochondrial dysfunction and NLRP3 activation. Targeted inhibition of CD49a
Huanpeng Lu, Yunmin Zhu, Xi Wang, Zelin Wu, Zijian Xu, Rongqing Chen, Yanwu Guo   +6 more
wiley   +1 more source

Inappropriate cervical injection of radiotracer for sentinel node mapping in a uterine cervix cancer patient: importance of lymphoscintigraphy and blue dye injection [PDF]

Asia Oceania Journal of Nuclear Medicine and Biology, 2014
Herein, we report a case of sentinel lymph node mapping in a uterine cervix cancer patient, referring to the nuclear medicine department of our institute. Lymphoscintigraphy images showed inappropriate intra‐cervical injection of radiotracer.
Sima Kadkhodayan, Elham Hosseini Farahabadi, Zohreh Yousefi, Malihe Hasanzadeh, Ramin Sadeghi   +4 more
doaj  

Sentinel Node Biopsy in Young Patients with Atypical Melanocytic Tumors of the Head and Neck

OTO Open, 2019
Objective To examine the diagnostic value of the sentinel lymph node biopsy in pediatric through young adult head and neck melanocytic tumors of unknown malignant potential. Study Design Retrospective case series.
David Pfau, Akina Tamaki MD, Kathryn R. Hoppe MD, Kord Honda MD, Rod Rezaee MD, Chad A. Zender MD   +5 more
doaj   +1 more source

Sentinel lymph node biopsy in early stage cervical cancer: A meta‐analysis

Cancer Medicine, 2021
Background The aim of this study was to determine the specific side detection rate of the sentinel lymph node biopsy and the accuracy in predicting lymph node metastasis in early stage cervical cancer.
Xinyue Zhang, Bingting Bao, Sixue Wang, Mingyu Yi, Li Jiang, Xiaoling Fang   +5 more
doaj   +1 more source

Monocyte‐Differentiation‐Activated Fluorescent “Scout” Probe for Precise in Vivo Detection of Vulnerable Plaque

Advanced Science, EarlyView.
An innovative monocyte‐differentiation‐activated fluorescent “scout” probe (MDAF) leverages the inherent chemotaxis of monocytes toward vulnerable plaques (VAP) to enable efficient targeted delivery while achieving spatiotemporally controllable activation of its AIE fluorescent signals with the dynamic differentiation of monocytes, providing an ...
Zechuan Li, Jiankai Dong, Zhengkun Liu, Chaoke Zhang, Jisen Li, Ying Tao, Ding Yang, Yansong Liu, Haoting Chen, Lu Liu, Jingsen Ji, Feng Cao, Dan Ding, Qian Liu, Chenxing Fu, Weisheng Guo   +15 more
wiley   +1 more source

The Accuracy of Sentinel Lymph Node Biopsy Compared with Axillary Lymph Node Dissection in Breast Cancer

Middle East Journal of Cancer, 2011
Background: Sentinel lymph node biopsy is used as an accurate staging procedure to detect early breast cancer. Several studies have documented that sentinel lymph node biopsy can accurately determine the status of axillary nodes.
Abdolrasul Talei, Ali Azimi, Sedigheh Tahmasebi, Zeinab Zakeri   +3 more
doaj  

Sentinel lymph node biopsy: Sentinel node technique has drawbacks [PDF]

BMJ, 2004
EDITOR—Among the possible drawbacks of sentinel node biopsy, discussed by Kell and Kerin,1 is the risk of false positive findings because of reactive lymph node swelling in the biopsy site. Periodic follow up of the sampled lymph node area has become a common practice after sentinel node …
openaire   +1 more source

From the Gut to the Brain: Microplastic‐Associated Neurovascular Dysfunction and Implications for Stroke Risk

Advanced Science, EarlyView.
Chronic oral exposure to microplastics may disrupt gut microbiota homeostasis and intestinal barrier integrity, potentially engaging the gut–brain axis and systemic inflammatory responses. These alterations may be associated with impaired blood–brain barrier function, cerebral microvascular dysfunction, and enhanced endothelial inflammation, pro ...
Hongxing Wang, Yujiao He, Pei Zou, Xiaoyi Wang, Gang Peng, Xiangying Deng   +5 more
wiley   +1 more source

iTRAQ proteomics of sentinel lymph nodes for identification of extracellular matrix proteins to flag metastasis in early breast cancer [PDF]

, 2022
Sheetal Pathania, Mohd Imran Khan, Sabyasachi Bandyopadhyay, Suneet Shekhar Singh, Komal Rani, Tanvi Ramesh Parashar, Jnaneshwari Jayaram, Piyush Ranjan Mishra, Anurag Srivastava, Sandeep Mathur, Smriti Hari, Perumal Vanamail, Gururao Hariprasad   +12 more
openalex   +1 more source

Photoacoustic Microscopy for Multiscale Biological System Visualization and Clinical Translation

Advanced Science, EarlyView.
Photoacoustic microscopy (PAM) is a powerful biomedical imaging tool renowned for its non‐invasiveness and high resolution. This review synthesizes recent technological advances and highlights their broad applications from cellular and organ‐level to whole‐animal imaging.
Tingting Wang, Jiali Chen, Liming Nie, Honghui Li   +3 more
wiley   +1 more source