Results 81 to 90 of about 1,465,858 (395)

Harnessing the Immunomodulation of UV‐Exposed Keratinocyte Extracellular Vesicles for Inflammatory Disorder Treatment

open access: yesAdvanced Science, EarlyView.
Adopting a paradigm shift that transforms a known health hazard as a potential therapeutic asset, a novel therapeutic strategy is set out to investigate for inflammatory conditions by leveraging immunosuppressive properties of UV‐irradiated keratinocytes.
Lu Liu   +16 more
wiley   +1 more source

Sentinel node staging for breast cancer: Intraoperative molecular pathology overcomes conventional histologic sampling errors [PDF]

open access: yes, 2007
BACKGROUND: When sentinel node dissection reveals breast cancer metastasis, completion axillary lymph node dissection is ideally performed during the same operation. Intraoperative histologic techniques have low and variable sensitivity.
Beitsch, Peter   +11 more
core   +2 more sources

PFKFB2‐Driven Glycolysis Promotes Dendritic Cell Maturation and Exacerbates Acute Lung Injury

open access: yesAdvanced Science, EarlyView.
Paraquat (PQ) or lipopolysaccharide (LPS) exposure activates the HIF‐1α–PFKFB2 pathway, driving glycolysis in dendritic cells (DCs). This metabolic shift enhances DC maturation and immune activation, exacerbating acute lung injury (ALI). This study demonstrates that PFKFB2‐driven glycolytic reprogramming in DCs plays a critical role in the pathogenesis
Ding Yuan   +17 more
wiley   +1 more source

Lymphoscintigraphy and triangulated body marking for morbidity reduction during sentinel node biopsy in breast cancer [PDF]

open access: yes, 2005
Current trends in patient care include the desire for minimizing invasiveness of procedures and interventions. This aim is reflected in the increasing utilization of sentinel lymph node biopsy, which results in a lower level of morbidity in breast cancer
Kim, Chun K   +6 more
core   +2 more sources

Are 3 Sentinel Nodes Sufficient? [PDF]

open access: yesArchives of Surgery, 2007
It has recently been proposed that only 3 sentinel lymph nodes (SLNs) are required for an adequate SLN biopsy. Others have advocated removing all nodes that are blue, hot, at the end of a blue lymphatic channel, or palpably suspicious or that have radioactive counts of 10% or greater of the most radioactive SLN. Our objective was to determine the false-
Kelly M. McMasters   +7 more
openaire   +2 more sources

Bacterial Foreignization Nanosystem Elicits Multi‐Phenotypic T Cells for Antitumor Immunity

open access: yesAdvanced Science, EarlyView.
In this study, a comprehensive strategy for tumor immunogenicity reshaping is implemented, in which all adjuvanticity, antigenicity, and reactogenicity of tumor cells are highly improved by an engineered bacterial nanosystem through a selective membrane fusion process. The resulting foreignized tumor cells evoke potent innate immune responses, inducing
Wan‐Ru Zhuang   +10 more
wiley   +1 more source

A Wait-Free Stack

open access: yes, 2015
In this paper, we describe a novel algorithm to create a con- current wait-free stack. To the best of our knowledge, this is the first wait-free algorithm for a general purpose stack.
Aggarwal, Pooja   +2 more
core   +1 more source

Viral‐Directed Augmentation of Kupffer Cell Cross‐Presentation Provokes Antitumor Immunity Against Liver Metastasis

open access: yesAdvanced Science, EarlyView.
Targeting Kupffer cells (KC) with a single intravenous infusion of the oncolytic virus VSV‐M51R rather than VSV‐WT induces effective tumor regression in various types of liver metastatic cancers in mice. VSV‐M51R promotes KC proliferation and enhances their antigen cross‐presentation capacity without compromising viability, leading to the induction of ...
Chen Chen   +8 more
wiley   +1 more source

Combined Methylene Blue Dye andRadioactive Tracer Technique for Sentinel Lymph Node Localization in Early Breast Cancer

open access: yesMiddle East Journal of Cancer, 2010
Background: Sentinel lymph node biopsy is a technique used to identify the axillary node most likely to contain tumor cells that have metastasized from a primarycarcinoma of the breast.
Abdolrasoul Talei   +2 more
doaj  

Sentinel Lymph Node Biopsy or Detection of Micrometastasis in Bone Marrow: Which Might Be an Alternative to Axillary Lymph Node Dissection in Breast Cancer Patients?

open access: yesAsian Journal of Surgery, 2004
Axillary lymph node status has limited prognostic significance in breast cancer patients and much improvement can be made. Sentinel lymph node biopsy is emerging as an alternative to axillary lymph node dissection for staging, but its prognostic ...
Li Zhu, Chi Kei Lam, Louis W.C. Chow
doaj   +1 more source

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