Results 81 to 90 of about 1,465,858 (395)
Adopting a paradigm shift that transforms a known health hazard as a potential therapeutic asset, a novel therapeutic strategy is set out to investigate for inflammatory conditions by leveraging immunosuppressive properties of UV‐irradiated keratinocytes.
Lu Liu+16 more
wiley +1 more source
Sentinel node staging for breast cancer: Intraoperative molecular pathology overcomes conventional histologic sampling errors [PDF]
BACKGROUND: When sentinel node dissection reveals breast cancer metastasis, completion axillary lymph node dissection is ideally performed during the same operation. Intraoperative histologic techniques have low and variable sensitivity.
Beitsch, Peter+11 more
core +2 more sources
PFKFB2‐Driven Glycolysis Promotes Dendritic Cell Maturation and Exacerbates Acute Lung Injury
Paraquat (PQ) or lipopolysaccharide (LPS) exposure activates the HIF‐1α–PFKFB2 pathway, driving glycolysis in dendritic cells (DCs). This metabolic shift enhances DC maturation and immune activation, exacerbating acute lung injury (ALI). This study demonstrates that PFKFB2‐driven glycolytic reprogramming in DCs plays a critical role in the pathogenesis
Ding Yuan+17 more
wiley +1 more source
Lymphoscintigraphy and triangulated body marking for morbidity reduction during sentinel node biopsy in breast cancer [PDF]
Current trends in patient care include the desire for minimizing invasiveness of procedures and interventions. This aim is reflected in the increasing utilization of sentinel lymph node biopsy, which results in a lower level of morbidity in breast cancer
Kim, Chun K+6 more
core +2 more sources
Are 3 Sentinel Nodes Sufficient? [PDF]
It has recently been proposed that only 3 sentinel lymph nodes (SLNs) are required for an adequate SLN biopsy. Others have advocated removing all nodes that are blue, hot, at the end of a blue lymphatic channel, or palpably suspicious or that have radioactive counts of 10% or greater of the most radioactive SLN. Our objective was to determine the false-
Kelly M. McMasters+7 more
openaire +2 more sources
Bacterial Foreignization Nanosystem Elicits Multi‐Phenotypic T Cells for Antitumor Immunity
In this study, a comprehensive strategy for tumor immunogenicity reshaping is implemented, in which all adjuvanticity, antigenicity, and reactogenicity of tumor cells are highly improved by an engineered bacterial nanosystem through a selective membrane fusion process. The resulting foreignized tumor cells evoke potent innate immune responses, inducing
Wan‐Ru Zhuang+10 more
wiley +1 more source
In this paper, we describe a novel algorithm to create a con- current wait-free stack. To the best of our knowledge, this is the first wait-free algorithm for a general purpose stack.
Aggarwal, Pooja+2 more
core +1 more source
Targeting Kupffer cells (KC) with a single intravenous infusion of the oncolytic virus VSV‐M51R rather than VSV‐WT induces effective tumor regression in various types of liver metastatic cancers in mice. VSV‐M51R promotes KC proliferation and enhances their antigen cross‐presentation capacity without compromising viability, leading to the induction of ...
Chen Chen+8 more
wiley +1 more source
Background: Sentinel lymph node biopsy is a technique used to identify the axillary node most likely to contain tumor cells that have metastasized from a primarycarcinoma of the breast.
Abdolrasoul Talei+2 more
doaj
Axillary lymph node status has limited prognostic significance in breast cancer patients and much improvement can be made. Sentinel lymph node biopsy is emerging as an alternative to axillary lymph node dissection for staging, but its prognostic ...
Li Zhu, Chi Kei Lam, Louis W.C. Chow
doaj +1 more source