Results 111 to 120 of about 4,607,292 (321)

Resilient Calvarial Bone Marrow Supports Retinal Repair in Type 2 Diabetes

Advanced Science, EarlyView.
Skull bone (calvarium) marrow in diabetic mice stay structurally intact and keeps making blood cells, unlike the bone marrow of the leg bones. The skull marrow is exposed to cerebrospinal fluid (CSF), which contains protective molecules called oxysterols.
Bright Asare‐Bediako, Sergio Li Calzi, Julia G. Behnsen, Ram Prasad, Magdalena Blaszkiewicz, Yvonne Adu‐Rutledge, Robert F. Rosencrans, Jason L. Floyd, Ashley Rennhack, Denise Stanford, Anna Lin, Todd A. Lydic, Carl M. Sheridan, Michael E. Boulton, Kristy L. Townsend, Julia V. Busik, Maria B. Grant   +16 more
wiley   +1 more source

Influenza and Other Respiratory Virus Weekly Activity Report, May 29, 2009, revised Week 20 [PDF]

, 2009
Weekly report of the Iowa Influenza Surveillance Network produced by the Iowa Department of Public ...

core  

Immunoaffinity‐Mimetic Assembly of Peptide‐Aptamer Conjugates and Stem Cell‐Derived Exosomes into Hierarchical Microgels for Spinal Cord Injury Repair

Advanced Science, EarlyView.
Inspired by antibody‐antigen binding, this study develops an unprecedented immunoaffinity‐mimetic assembly strategy, with Peptide‐AptCD63 conjugates acting as antibody surrogates binding CD63 epitopes on mesenchymal stem cell‐derived exosomes. This creates a hierarchical microstructure intended to synergistically integrate antioxidative and anti ...
Dantong Zheng, Yuxin Bai, Zhibo Liu, Zinan Zhao, Yiming Kong, Yao Xu, Qi Jia, Rongrong Zhu, Yong Hu   +8 more
wiley   +1 more source

Lymphoscintigraphy Defines New Lymphatic Pathways from Cutaneous Melanoma Site: Clinical Implications and Surgical Management

Radiology Research and Practice, 2011
Sentinel lymph node biopsy is commonly applied as staging procedure of regional lymph nodes in patients with cutaneous melanoma. Dynamic lymphoscintigraphy defines the lymphatic pathways from a primary melanoma site and allows to identify the node ...
Ugo Marone, Luigi Aloj, Gianluca Di Monta, Corrado Caracò   +3 more
doaj   +1 more source

Plant structural complexity and mechanical defenses mediate predator-prey interactions in an odonate-bird system. [PDF]

, 2017
Habitat-forming species provide refuges for a variety of associating species; these refuges may mediate interactions between species differently depending on the functional traits of the habitat-forming species.
Grof-Tisza, Patrick, Heath, Sacha K, Karban, Richard, LoPresti, Eric   +3 more
core   +2 more sources

ACSL1‐Dependent Microglial Lipoimmunometabolic Reprogramming Underlies Cognitive Deficits in Alcohol Use Disorder

Advanced Science, EarlyView.
This study reveals that chronic alcohol exposure selectively upregulates ACSL1 expression in prefrontal cortical microglia, driving lipid metabolism reprogramming and lipid droplet accumulation, which activates the NLRP3 inflammasome and sustains neuroinflammation. To reverse this process, a dual‐targeted lipid nanoparticle, siACSL1@LNP‐MR, is designed
Liang Hao, Xing‐Rui Cao, Bai‐Qiang Li, Fu‐Ying Zhao, Jia‐Mei Wang, Rui‐Kang Gao, Zhi‐Peng Cao, Zhen‐Xian Du, Hua‐Qin Wang   +8 more
wiley   +1 more source

Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms [PDF]

, 2017
Coronary artery disease (CAD) is a leading cause of morbidity and mortality worldwide. Although 58 genomic regions have been associated with CAD thus far, most of the heritability is unexplained, indicating that additional susceptibility loci await ...
A Schröder, Abdulla al Shafi Majumder, Adam S Butterworth, Alex P Reiner, Anders Malarstig, Andrew D Johnson, Anne Justice, Anne Tybjærg-Hansen, AP Levy, AP Morris, AP Reiner, Arshed A Quyyumi, Asif Rasheed, AV Segrè, Benjamin B Sun, BF Voight, BL Harry, BP Fairfax, Børge G Nordestgaard, C Moore, Cara L Carty, Carl J Pepine, Chao A Hsiung, Charles Kooperberg, CJ Willer, D Qu, Daniel F Freitag, Daniel J Rader, Daniel R Barnes, Danish Saleheen, Devin Absher, Dewan S Alam, Dirk S Paul, DM Greenawalt, E Grundberg, EE Schadt, Elias L Salfati, Emanuele Di Angelantonio, Eric B Fauman, Eric Boerwinkle, F Innocenti, GA Roth, GR Abecasis, H Kirsten, H Lin, H Schunkert, Heribert Schunkert, HJ Westra, Hugh Watkins, I Holme, I-Te Lee, J Chen, J Dennis, J Erdmann, J Ernst, J Ernst, J Yang, Jeanette Erdmann, Jemma B Wilk, Jerome I Rotter, Joanna M M Howson, John A Spertus, John D Eicher, John Danesh, JR Privratsky, JR Staley, Julie A Johnson, Jyh-Ming J Juang, Kari E North, Katrine L Rasmussen, Kent D Taylor, Kristin Young, LD Ward, Lindsay L Waite, LM Boettger, Lucia A Hindorff, M Arnold, M Narahara, M Uhlen, M Uhlén, Mariaelisa Graff, N Franceschini, Nilesh J Samani, NJ Samani, NL Smith, Nora Franceschini, O Franzén, P Surendran, P Zanoni, Panos Deloukas, Philippe Frossard, Pia R Kamstrup, Praveen Surendran, R Goel, Rajiv Chowdhury, Ren-Hua Chung, Robin Young, Ron Do, S Purcell, Sekar Kathiresan, Stanley L Hazen, Steven Buyske, Sune F Nielsen, T Lappalainen, T Zeller, Themistocles L Assimes, Thomas Quertermous, TL Assimes, TM Teslovich, Tzung-Dau Wang, Ulrike Peters, V Nanda, W Tang, Wayne H H Sheu, Weang-Kee Ho, Wei Zhao, Wei-Yu Lin, Wen-Jane Lee, WJ Astle, X Zhang, X Zhou, Xiuqing Guo, Yi-Jen Hung, Yii-Der Ida Chen, Ying-Hsiang Chen, Z Wang, Å Johansson   +126 more
core   +2 more sources

Integrated monitoring and evaluation and environmental risk factors for urogenital schistosomiasis and active trachoma in Burkina Faso before preventative chemotherapy using sentinel sites

BMC Infectious Diseases, 2011
BackgroundOver 1 billion of the world's poorest inhabitants are afflicted by neglected tropical diseases (NTDs). Integrated control programmes aimed at tackling these debilitating NTDs have been recently initiated, mainly using preventative chemotherapy.
A. Koukounari, S. Touré, C. Donnelly, A. Ouédraogo, Bernadette Yoda, Césaire Ky, Martin Kaboré, E. Bosqué-Oliva, M. Basáñez, A. Fenwick, J. Webster   +10 more
semanticscholar   +1 more source

Cascade‐Responsive MXene@Cu‐MOF Heterostructure Integrates Antioxidant Activity, Infection Control, and Vascularization for Tracheal Repair

Advanced Science, EarlyView.
A cascade‐responsive MXene@Cu‐MOF/GelMA hydrogel is engineered as a “skeleton–backpack” platform for extensive tracheal repair. The MXene framework scavenges postoperative ROS and converts NIR light into mild hyperthermia, while the Cu‐MOF component provides pH/NIR‐responsive Cu2+ dosing for infection control, angiogenesis, and chondrogenesis.
Liang Guo, Yingran Shen, Jiaoyu Yi, Juanjuan Li, Ziming Wang, Erji Gao, Siqiang Zheng, Zhe‐Sheng Chen, Bo Tao   +8 more
wiley   +1 more source

Monitoring the South African National Antiretroviral Treatment Programme, 2003-2007: the IeDEA Southern Africa collaboration. [PDF]

, 2009
OBJECTIVES: To introduce the combined South African cohorts of the International epidemiologic Databases to Evaluate AIDS Southern Africa (IeDEA-SA) collaboration as reflecting the South African national antiretroviral treatment (ART) programme; to ...
Boulle, Andrew, Cornell, Morna, Davies, Mary-Ann, Eley, Brian, Fairall, Lara, Giddy, Janet, MacPhail, Patrick, Maxwell, Nicola, Mohapi, Lerato, Moultrie, Harry, Prozesky, Hans, Rabie, Helena, Technau, Karl, van Cutsem, Gilles, Wood, Robin   +14 more
core   +1 more source