Results 71 to 80 of about 36,594 (254)

De‐escalating radical surgery for select FIGO Stage I cervical cancer

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Four recent prospective trials demonstrated that de‐escalation of radical surgery for select patients with apparent low‐risk, FIGO Stage I cervical cancer does not compromise cancer‐related survival but does improve quality of life and provide the opportunity to preserve fertility.
Sara Moufarrij, Rene Pareja, Angélica Fletcher, Sarikapan Wilailak, Nadeem R. Abu‐Rustum, on behalf of the FIGO Committee on Women's Cancer   +5 more
wiley   +1 more source

Sentinel Surveillance: A Reliable Way To Track Antibiotic Resistance in Communities?

Emerging Infectious Diseases, 2002
We used population-based data to evaluate how often groups of randomly selected clinical laboratories accurately estimated the prevalence of resistant pneumococci and captured trends in resistance over time. Surveillance for invasive pneumococcal disease
Stephanie J. Schrag, Elizabeth R. Zell, Anne Schuchat, Cynthia G. Whitney   +3 more
doaj   +1 more source

Minimally Invasive Sampling for Molecular Profiling of Lymph Nodes Using a Modified Acupuncture Needle

iMetaMed, EarlyView.
Schematic illustration of the preparation of His@PDA@Needle, a modified acupuncture needle designed for minimally invasive sampling of lymph node‐derived DNA for molecular profiling. ABSTRACT Current clinical liquid biopsy approaches predominantly rely on blood‐derived biomarkers, which are often limited in sensitivity.
Baiping Cui, Mingyu Li, Pingzhu Zhou, Lihfeng Cheow, Hailong Ma, Dongdong Liu   +5 more
wiley   +1 more source

Sentinel surveillance system for early outbreak detection in Madagascar

BMC Public Health, 2010
Background Following the outbreak of chikungunya in the Indian Ocean, the Ministry of Health directed the necessary development of an early outbreak detection system.
Randrianarivo-Solofoniaina Armand, Ramanjato Robinson, Heraud Jean-Michel, Rakotomanana Fanjasoa, Andriamandimby Soa, Ravolomanana Lisette, Ratsitorahina Maherisoa, Raoelina Yolande, Randrianasolo Laurence, Richard Vincent   +9 more
doaj   +1 more source

Objective measures for sentinel surveillance in network epidemiology [PDF]

Physical Review E, 2018
Assume one has the capability of determining whether a node in a network is infectious or not by probing them. Then problem of optimizing sentinel surveillance in networks is to identify the nodes to probe such that an emerging disease outbreak can be discovered early or reliably. Whether the emphasis should be on early or reliable detection depends on
openaire   +3 more sources

Microbiome and aging: Trajectories of microbiome age across human ecosystems and their systemic effects

iMeta, EarlyView.
Microbiome age (MA) has emerged as an innovative biomarker of biological aging, reflecting host aging trajectories through dynamic alterations in microbial composition, function, and host–microbe interactions across multiple body ecosystems. Diverse computational strategies—including traditional machine learning, deep learning, and multi‐omics ...
Zhexin Ni, Jiaojiao Xie, Zhichun Zhang, Keming Zhang, Jie Ding, Mingyang Chang, Ying Su, Yunan Zhang, Mingfei Yao, Chengyuan Wang, Yan Yan, Wenjie Fang, Hainv Gao, Xuecong Tian, Yangshuo Li, Xinlin Zhu, Wen Zhang, Wanqing Liao, Gaoyuan Xu, Guojing Chen, Xiaoyi Lv, Chaoqin Yu, Weihua Pan, Vadim Molodtsov, Lanjuan Li, Yue Gao, Wei Zhou   +26 more
wiley   +1 more source

The rationale for integrated childhood meningoencephalitis surveillance: a case study from Cambodia

Bulletin of the World Health Organization, 2009
PROBLEM: Recent progress in vaccine availability and affordability has raised prospects for reducing death and disability from neurological infections in children.
Sok Touch, John Grundy, Susan Hills, Manju Rani, Chham Samnang, Asheena Khalakdina, Julie Jacobson   +6 more
doaj  

Maternal and infant gut microbiome

iMeta, EarlyView.
The maternal–infant continuum involves critical windows of host–microbiota co‐adaptation. Preconception, maternal and paternal microbiomes modulate immunity and reproduction. During pregnancy, a gut–placenta axis emerges, where microbial metabolites influence fetal growth or contribute to complications like gestational diabetes mellitus (GDM ...
Huidi Wang, Felicia Tin, Hui Chen, Fuxin Jiao, Min Wu, Shanshan Sun, Lisha Lin, Die Li, Huimin Zheng, Zhenxin Niu, Mengyao Lan, Bahtiyar Yilmaz, Johan G. Eriksson, Mengjia Wang, Andrew Macpherson, Jose C. Clemente, Jia Xu, Ri‐hua Xie, Xiaojiao Zheng, Tao Zhou, Jinfeng Wang, Wei Shen, Bing Huang, Xia Chen, Hai Li, Yan He   +25 more
wiley   +1 more source

An integrated framework for modelling respiratory disease transmission and designing surveillance networks using a sentinel index

Royal Society Open Science
Defining epidemiologically relevant placements for sentinel units is critical for establishing effective health surveillance systems. We propose a novel methodology to identify optimal sentinel unit locations using network approaches and metapopulation ...
Dérick G. F. Borges, Eluã R. Coutinho, Daniel C. P. Jorge, Marcos E. Barreto, Pablo I. P. Ramos, Manoel Barral-Netto, Alvaro L. G. A. Coutinho, Luiz Landau, Suani T. R. Pinho, Roberto F. S. Andrade   +9 more
doaj   +1 more source

The T‐Cell Response Mechanism in Human Papillomavirus‐Associated Cervical Cancer and New Strategies for Immunotherapy

iNew Medicine, EarlyView.
ABSTRACT Human papillomavirus (HPV) is a double‐stranded DNA virus that infects human skin and mucosal tissues exclusively. The German scientist Harald zur Hausen was awarded the 2008 Nobel Prize in Physiology or Medicine for his discovery of the link between HPV infection and cervical cancer.
Fang Zhu, Farah Nazir, Ying Zhou, Yuhua Shang, Hongliang He, Tengchuan Jin   +5 more
wiley   +1 more source