Results 171 to 180 of about 461,298 (313)

DDX21 Enhances Radiosensitivity in Head and Neck Squamous Cell Carcinoma by Suppressing MK2‐Mediated DNA Damage Response

Advanced Science, EarlyView.
DDX21 suppresses MK2 activation by directly inhibiting Thr334 phosphorylation in a p38‐independent manner, thereby impairing DNA damage response. Clinically, patients with well‐differentiated tumors exhibiting high DDX21 expression are more likely to benefit from adjuvant radiotherapy, whereas those with low DDX21 levels are predisposed to ...
Tianru Yang, Ting Shen, Yanfang Qiu, Wei Zhang, Ziran Zheng, Jiayi Sun, Yuedi Yao, Mianfeng Yao, Jiang Li   +8 more
wiley   +1 more source

The gap between having and using: socioeconomic inequalities in long-lasting insecticidal net coverage among children and adolescents in rural Guinea. [PDF]

Trop Med Health
Toure AA, Sidibe S, Colombe S, Magassouba AS, Paviotti A, Kreppel K, Bottieau E, Kaba MP, Beavogui AH, Delamou A, Kouanda S.   +10 more
europepmc   +1 more source

Multimodal Imaging of Hypoxia, Metabolism and pH in Feline Sarcoma Using Hyperpolarized 13C MRI and PET

Advanced Science, EarlyView.
This work presents a clinically deployable simultaneous PET/MRI workflow which integrates hyperpolarized 13C imaging of metabolism and extracellular pH with [18F]FMISO PET to characterize hypoxia, acidosis, and metabolic reprogramming in feline sarcoma.
Martin Grashei, Tanja Groll, Stephanie Kahl, Silke Baer, Elisabeth Bliemsrieder, Frits H. A. van Heijster, Andre Wendlinger, Pascal Wodtke, Jorge Cabello, Susan Notohamiprodjo, Christian Lohrmann, Markus Schwaiger, Wolfgang A. Weber, Katja Steiger, Andrea Meyer‐Lindenberg, Johannes Hirschberger, Christine Baumgartner, Franz Schilling   +17 more
wiley   +1 more source

Intergenerational socioeconomic mobility and adulthood all-cause mortality in the Hispanic community health study/study of Latinos. [PDF]

Am J Epidemiol
Whalen AM, Ma W, Filigrana Villegas PA, Perreira KM, Cai J, Cordero C, Daviglus ML, Kaplan RC, Lee DJ, Llabre MM, Penedo FJ, Pichardo MS, Pirzada A, Suglia SF, Gallo LC, Isasi CR.   +15 more
europepmc   +1 more source

PULSATE SEP

First version of PULSATE SEP as unique access entrance which will support the internal cooperation and communication within PULSATE, the provision of services, deployment of digital tools and the execution of the experiments.
openaire   +1 more source

SEP: Source Extractor as a library [PDF]

The Journal of Open Source Software, 2016
openaire   +1 more source

Plant Metabolites Screening Identifies 7‐epi‐10‐Deacetyltaxol Inhibiting Cell Division by Interfering With the Cell Cycle and Microtubule Organization

Advanced Science, EarlyView.
In this study, an efficient screening system is developed for plant metabolites to find a compound, 7‐epi‐10‐deacetyltaxol, inhibits tissue elongation. It suppresses plant growth through brassinosteroid and microtubule pathways. It is later applied to animal cells and human tumor organoids, resulting in similar cell division suppression. These findings
Yan‐Jie Zhang, Yu‐Xuan Bai, Geng G. Tian, Bin Zhang, Ding‐Yi Lu, Qing‐Ping Yao, Wen‐Hao Tian, Xiao‐Na Wei, Jing‐Ting Yang, Ze‐Yu Xiong, Yi Lu, Yu‐Tong Jiang, Chun‐Hui Cai, Yu‐Ming Lu, Xian‐Qing Jia, Li‐Li Jing, Bao‐Jun Yang, Ying‐Xin Qi, Xin‐Xin Han, Ji Wu, Wen‐Hui Lin   +20 more
wiley   +1 more source

Tailoring in eHealth lifestyle interventions targeting people with cardiometabolic conditions and lower socioeconomic position: A scoping review. [PDF]

PLOS Digit Health
Van Mellaert S, Kreuzberg MS, Ten Klooster I, van Beijnum BF, van Rijn JN, Tabak M.   +5 more
europepmc   +1 more source

Aspirin‐Derived Salicyl‐CoA Drives Histone Lysine Salicylation Regulated by CBP and SIRT2

Advanced Science, EarlyView.
Aspirin‐derived salicyl‐CoA serves as a previously unrecognized acyl donor for protein lysine salicylation. This study identifies histone lysine salicylation as a reversible epigenetic modification regulated by CBP and SIRT2, expanding the biochemical actions of aspirin beyond its canonical acetylation‐dependent mechanisms and providing a new framework
Facai Zhang, Chuanzan Zhou, Jiaoyan He, Pengpeng Huang, Rong Zhang, Huan Hu, Meng Jiao, Linyi Hu, Feng Liu, Xiaolong Qi, Xiang He, Yunkai Yang, Y Eugene Chinn, Dechao Feng, Dahong Zhang, Qi Zhang   +15 more
wiley   +1 more source

A biosensor platform for scalable and live detection of PYY hormone production from enteroendocrine cells with single-event resolution. [PDF]

J Biol Chem
Hirdaramani A, Frost G, Hanyaloglu AC.
europepmc   +1 more source