Results 181 to 190 of about 461,298 (313)

Extracellular Vesicle Packaged TDP43 Derived From ECs Exacerbates Cigarette Tar‐Related Atherosclerosis Progression via Enhancing Macrophage Extracellular Traps

Advanced Science, EarlyView.
Cigarette tar triggers EC‐derived EVs carrying TDP43, which binds VDAC1 to boost MAMs, mitochondrial Ca2+ overload, and METs formation in macrophages, accelerating smoking‐related AS progression, while retinoic acid binds TDP43 to block this pathogenic cascade.
Xinxin Zhu, Yuwu Chen, Wei Meng, Biyi Xu, Junke Mou, Xiaolin Liu, Mengyang Wang, Qishuo Gu, Qianhui Sun, Man Li, Chen Zhao, Ming Zeng, Ying Lv, Boling Yi, Sheng Qu, Xiaoxuan Bai, Ji Li, Xing Luo, Sining Hu, Bo Yu, Haibo Jia   +20 more
wiley   +1 more source

Effect of 5.25% Sodium Hypochlorite Enamel Deproteinization on the Initial Shear Bond Strength and Resin Penetration in the Enamel of Orthodontic Brackets Bonded With a Self-Etching Primer: An In Vitro Study on Human Bicuspids. [PDF]

Int J Dent
Kebaïli N, Fourneron M, Mati M, Salehi H, Barthelemi S, Tannouri Z.   +5 more
europepmc   +1 more source

Lipid Metabolic Dysregulation Driven by OSMR Mutations Underlies Amyloidogenesis in Primary Localized Cutaneous Amyloidosis

Advanced Science, EarlyView.
OSMR mutations disrupt STAT5 signaling and AKR1B10‐mediated lipid metabolism, leading to lipid accumulation and protein aggregation in keratinocytes. This metabolic reprogramming drives amyloid deposition in primary localized cutaneous amyloidosis, revealing a mechanistic link between lipid dysregulation and amyloidogenesis.
Huiting Liu, Wen Zheng, Chao Yang, Tao Yang, Qiuyu Chen, Ping Lu, Huan Yang, Jun Liu, Bin Yang   +8 more
wiley   +1 more source

Gender, age, and socioeconomic position-specific associations between illness perception and diabetes-related distress: cross-sectional analysis among people with type 2 diabetes. [PDF]

Front Endocrinol (Lausanne)
Landstra EN, de Klerk F, van Schalkwijk D, Jansen H, Valke LLFG, Smeets T, Mark RE, Soedamah-Muthu SS.   +7 more
europepmc   +1 more source

Connection of the biogas power plant Motvarjevci in a 20 kV grid [PDF]

, 2008
Sep, Jure
core  

β‐Adducin Restrains PLA2G4A‐Dependent Lysosomal Membrane Permeabilization and Neuronal Death in Ischemic Stroke

Advanced Science, EarlyView.
This study identifies β‐adducin as a regulator of lysosomal integrity in ischemic neurons. Ischemia‐associated FTO loss increases m6A modification and destabilizes Add2 mRNA, reducing β‐adducin expression and promoting PLA2G4A accumulation at lysosomes.
Hui‐qin Li, Pin‐yi Liu, Dan Wu, Fei‐yu Ma, Yi Bai, Sheng‐nan Xia, Hai‐yan Yang, Xin‐yu Bao, Yun Xu, Xiang Cao   +9 more
wiley   +1 more source

Association Between Socioeconomic Position and Diagnosis, Treatment and Survival of Patients With Stage I-III Rectal Cancer in the Netherlands. [PDF]

Int J Cancer
de Vries SEN, van Erning FN, Aarts MJ, Couwenberg AM, Galanos LJK, van Hellemond IEG, de Hingh IHJT, Lurvink R, Nagtegaal ID, de Wilt JHW, Elferink MAG.   +10 more
europepmc   +1 more source

Structural Variants in the Human Genome Associated With Gut Microbiome and Blood Metabolic Traits With Potential Causal Links

Advanced Science, EarlyView.
Based on a multi‐omics cohort of 2002 individuals comprising high‐depth whole‐genome and metagenomic sequencing data, blood metabolites, and detailed questionnaires, we identified 138 859 high‐confidence SVs, uncovering 36 significant SV–microbiome associations and 48 SV–blood metabolite associations.
Qun Zhou, Keqing Wang, Junhong Chen, Haoyu Wang, Xinjiang Tan, Xuanlin Huang, Zhiyin Lin, Xun Xu, Xin Jin, Shaoqiao Zhang, Liang Xiao, Yuanqiang Zou, Tao Zhang, Xiaomin Liu   +13 more
wiley   +1 more source

Detection of Japanese encephalitis virus in <i>Culex tritaeniorhynchus</i> following the 2024 Noto Peninsula earthquake, Japan. [PDF]

Parasite Epidemiol Control
Mochizuki K, Oikawa Y, Murakami M.
europepmc   +1 more source

Microstructure Evolution in Dry‑Coated Sulfidic All‐Solid‐State Battery Cathodes: Investigating Core–Shell Particle Morphology

Advanced Science, EarlyView.
Mixing method directly governs interface engineering and electrode morphology during the dry coating of all‐solid‐state battery cathodes. While high‐shear batch mixing yields poor electrode quality and lacks core–shell‐like features, continuous extruder mixing enables strong binder fibrillation and a core–shell‐like coating between the active material ...
Michael Wolf, Aaron Stoeckle, Rebecca Wilhelm, Maximilian A. Plass, Milad Hosseini, Johannes Kriegler, Korbinian Huber, Simon Lux   +7 more
wiley   +1 more source