Results 111 to 120 of about 8,586,627 (344)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Experimental Studies of Elements from the Functional Intermetallic Cu-Al-Mn for Construction of a Heat Engine and Power Plant [PDF]

open access: yesProblems of the Regional Energetics
The main objectives of the work are to study the thermomechanical characteristics and establish the patterns of reactive force generation by elements made of functional Cu-Al-Mn intermetallic compounds for their further use in heat engines of electrical ...
Kozyrskyi V., Bunko V.
doaj   +1 more source

Numerical simulation of separated flows [PDF]

open access: yes
A new numerical method, based on the Vortex Method, for the simulation of two-dimensional separated flows, was developed and tested on a wide range of gases. The fluid is incompressible and the Reynolds number is high. A rigorous analytical basis for the
Baganoff, D.   +2 more
core   +1 more source

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

open access: yes
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana   +8 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Prevalence of Emotional and Behavioral Difficulties and Associated Factors Among Adolescents with Divorced or Separated Parents in Vietnam: A cross-sectional study using the SDQ-25

open access: yesAsia Pacific Journal of Health Management
Objectives: This study evaluates the prevalence of emotional and behavioral difficulties using the SDQ-25 self-report version and identifies factors associated with these difficulties among adolescents in urban Vietnam with divorced or separated parents.
Tran Binh Thang   +8 more
doaj  

Joint ML calibration and DOA estimation with separated arrays

open access: yes, 2016
This paper investigates parametric direction-of-arrival (DOA) estimation in a particular context: i) each sensor is characterized by an unknown complex gain and ii) the array consists of a collection of subarrays which are substantially separated from ...
Boyer, Rémy   +4 more
core   +3 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

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