Results 101 to 110 of about 2,215,497 (314)

Adiabatic wall temperature and heat transfer coefficient influenced by separated supersonic flow

open access: yesEPJ Web of Conferences, 2017
Investigations of supersonic air flow around plane surface behind a rib perpendicular to the flow direction are performed. Research was carried out for free stream Mach number 2.25 and turbulent flow regime - Rex>2·107.
Leontiev Alexander   +3 more
doaj   +1 more source

Connotation, application and prospect of the fourth-generation separated layer water injection technology

open access: yesPetroleum Exploration and Development, 2017
The fourth-generation separated layer water injection technology was studied aiming at problems existing in current separated layer water-flooding technologies and production requirements.
He LIU   +4 more
doaj   +1 more source

Supersonic burning in separated flow regions [PDF]

open access: yes
The trough vortex phenomena is used for combustion of hydrogen in a supersonic air stream. This was done in small sizes suitable for igniters in supersonic combustion ramjets so long as the boundary layer displacement thickness is less than 25% of the ...
Zumwalt, G. W.
core   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

An analysis of the crossover between local and massive separation on airfoils [PDF]

open access: yes
Massive separation on airfoils operating at high Reynolds number is an important problem to the aerodynamicist, since its onset generally determines the limiting performance of an airfoil, and it can lead to serious problems related to aircraft control ...
Barnett, M., Carter, J. E.
core   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

Wind-Induced Ventilation Based on the Separated Flow Region

open access: yesJournal of Applied Fluid Mechanics, 2016
An experimental investigation was conducted to study the potential use of the pressure reduction within the separated flow region followed by the wake at the leeward direction of a solid surface in natural ventilation of buildings.
Mostafa Rahimi, Mehdi Javadi Nodeh
doaj  

An analysis method for multi-component airfoils in separated flow [PDF]

open access: yes
The multi-component airfoil program (Langley-MCARF) for attached flow is modified to accept the free vortex sheet separation-flow model program (Analytical Methods, Inc.-CLMAX).
Duorak, F. A., Maskew, B., Rao, B. M.
core   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

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