Results 131 to 140 of about 2,215,497 (314)
Differential analysis for the turbulent boundary layer on a compressor blade element (including boundary-layer separation) [PDF]
A two-dimensional differential analysis is developed to approximate the turbulent boundary layer on a compressor blade element with strong adverse pressure gradients, including the separated region with reverse flow.
Schmidt, J. F., Todd, C. A.
core +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Navier-Stokes and Euler solutions for lee-side flows over supersonic delta wings. A correlation with experiment [PDF]
An Euler flow solver and a thin layer Navier-Stokes flow solver were used to numerically simulate the supersonic leeside flow fields over delta wings which were observed experimentally. Three delta wings with 75, 67.5, and 60 deg leading edge sweeps were
Mcmillin, S. Naomi +2 more
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Flow Analysis of Space Shuttle Feed Line 17-inch Disconnect Valve [PDF]
, 1988 A steady incompressible three-dimensional viscous flow analysis has been conducted for the Space Shuttle External Tank/Orbiter propellant feed line disconnect flapper valves with upstream elbows.
Kandula, Max, Pearce, Daniel
core +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
MODELING CONTROL PROCESSES OF UNSTEADY SEPARATED FLOW IN THE NEAR WAKE
Научный вестник МГТУ ГА, 2016 The paper shows possibility of implementing the open source CFD software package OpenFOAM for calculation of unsteady vortex flows in researching of flow past cylinder with plate.
V. T. Kalugin +2 more
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A new flow model for highly separated airfoil flows at low speeds [PDF]
An analytical model for separated airfoil flows is presented which is based on experimentally observed physical phenomena. These include a free stagnation point aft of the airfoil and a standing vortex in the separated region.
Naik, S. N., Zumwalt, G. W.
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Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Научный вестник МГТУ ГА, 2017 For the time being, a combat-capable trainer aircraft has already been used as a light attack aircraft. The quality of mission effectiveness evaluation depends on the degree of relevance of mathematical models used.
S. A. Popov, Y. A. Gondarenko
doaj
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source