Results 71 to 80 of about 1,999,370 (297)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

[Texas Instruments Press Releases, May-December 1953]

open access: yes, 1953
1. Release dated May 23, 1953 is in regard to new office and plant facilities and additions to the Lemmon Avenue facility. 2. Release dated July 27, 1953 is in regard to new types of hermetically sealed transistors. 3. Release dated August 28, 1953 is in
Texas Instruments Incorporated
core  

Effect of Separated Instruments on Apical Seal of Root Canals Obturated with Different Techniques: An In-vitro Stereomicroscopic Study [PDF]

open access: yesJournal of Clinical and Diagnostic Research
Introduction: Practitioners often encounter challenges during root canal preparation, particularly with instrument separation. There is a need to understand how broken instruments interact with different obturation techniques.
Ashwini A Narayanan   +5 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Musical instrument sound source separation

open access: yes, 2009
The structured arrangement of sounds in musical pieces, results in the unique creation of complex acoustic mixtures. The analysis of these mixtures, with the objective of estimating the individual sounds which constitute them, is known as musical instrument sound source separation, and has applications in audio coding, audio restoration, music ...
openaire   +2 more sources

Retrieval of a separated instrument using Masserann technique

open access: yesJournal of Conservative Dentistry, 2008
The fracture of endodontic instruments is a procedural problem creating a major obstacle to normal routine therapy. The separated instrument, particularly a broken file, leads to metallic obstruction in the root canal and impedes efficient cleaning and shaping.
Thirumalai, Arun Kulandaivelu   +2 more
openaire   +3 more sources

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

[Texas Instruments Press Releases, November-December 1970]

open access: yes, 1970
1. Press release dated November 2, 1970 announces a leave of absence for assistant vice president Jack Kilby, during which time he will be working as an inventor. 2.
Texas Instruments Incorporated
core  

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