Results 81 to 90 of about 1,999,370 (297)

Indian Endodontic Society: Position statement on the management of separated instruments during root canal treatment

open access: yesEndodontology
This position statement on the management of separated instruments, endorsed by the Indian Endodontic Society, aims to provide a brief perspective on the challenges faced during shaping of the complex root canal system, and how the inadvertent separation
Aishwarya Vasudevan   +3 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Deep Learning-Based Detection of Separated Root Canal Instruments in Panoramic Radiographs Using a U2-Net Architecture

open access: yesDiagnostics
Background: Separated endodontic instruments are a significant complication in root canal treatment, affecting disinfection and long-term prognosis. Their detection on panoramic radiographs is challenging, particularly in complex anatomy or for less ...
Nildem İnönü   +5 more
doaj   +1 more source

Retrieval of separated instrument from the root canal using ultrasonics: Report of three cases

open access: yesEndodontology, 2019
One of the most frequent mishaps during root canal procedure is the separation of an endodontic instrument during biomechanical preparation. It prevents proper debridement of the canal apical to the fragment and compromises the success of the treatment ...
Ashtha Arya, Anshul Arora, Gourav Thapak
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Lawyers, Civil Law Notaries vs. Municipal Scriveners. A Particularity of Hungarian Legal History: the Private Activities of Scriveners

open access: yesJournal on European History of Law, 2018
Following the Austro-Hungarian Compromise legislation separated the justice system from public administration, however the regulation on the private activities of municipal scriveners remained unchanged. Lawyers and notaries requested the elimination of
Gábor Rokolya
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

[Texas Instruments Press Releases, April 1967]

open access: yes, 1967
1. Press release dated April 4, 1967 from Congresswoman Margaret M. Heckler announces the award of $7 million contract by the Nuclear Division of Union Carbide Corporation, for the continued production of nuclear fuel assemblies for the High Flux Isotope
Texas Instruments Incorporated
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Survey of recently separated parents [PDF]

open access: yes, 2013
This report presents the key findings from the Survey of Recently Separated Families 2012. This study examined the experiences of 6,119 parents who separated between 31 July 2010 and 31 December 2011.
John De Maio
core  

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