Results 141 to 150 of about 5,016,974 (324)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Estimation of Separable Representation in Psychophysical Experiments

open access: yes, 2005
Studying how individuals compare two given quantitative stimuli, say d1 and d2, is a fundamental problem. One very common way to address it is through ratio magnitude estimation, that is to ask individuals not to give values to d1 and d2 but rather to give their estimates of the ratio p = d1/d2 .
Bernasconi, M.   +2 more
openaire   +3 more sources

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

On the local Langlands correspondence for non-tempered representations [PDF]

open access: yes, 2013
Let G be a reductive p-adic group. We study how a local Langlands correspondence for irreducible tempered G-representations can be extended to a local Langlands correspondence for all irreducible smooth representations of G.
Solleveld, Maarten   +15 more
core   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Group representations

open access: yes, 1992
Part A: Background Material and Part B: Introduction to Group Representations and ...
Karpilovsky, G, Karpilovsky, Gregory
core  

Social representations, legitimacy and market change

open access: yes, 2018
The study illuminates the influence of cultural factors on change using social representations and institutional theory. The interaction between social representations and cultural- cognitive legitimacy in market change is exposed through a triangulation
Mwangi, V. Cocker, H. and Piacentini, M. G.,
core   +4 more sources

Differences in spatiotemporal dynamics for processing specific semantic categories: An EEG study

open access: yesScientific Reports
Semantic processing is an essential mechanism in human language comprehension and has profound implications for speech brain-computer interface technologies. Despite recent advances in brain imaging techniques and data analysis algorithms, the mechanisms
Trang Thi Le   +4 more
doaj   +1 more source

Domain-Specific Self-Supervised Contrastive Learning with Contrast-Aware Pair Refinement for Pathological Image Analysis

open access: yesBig Data Mining and Analytics
Deep learning offers notable promise for computational pathology, but its performance is constrained by the need for extensively annotated datasets, which are costly and laborious to produce.
Junjian Li   +4 more
doaj   +1 more source

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