Results 111 to 120 of about 277,425 (303)

Operation optimization of a membrane separation process through auto-controlling the permeate gas flux

open access: yes, 2007
Operating characteristics of a gas membrane separation process were described qualitatively. Various methods of controlling the permeate gas flux were compared.
Shao, Cheng, Wang, Lei, Wang, Hai
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Structural Insights Into Aluminum‐Doped Manganese Dioxides as Promising Materials for Direct Lithium Extraction: Modeling and Mechanism Study

open access: yesAdvanced Materials Interfaces
This study aimed to provide new insights into lithium (Li) sorption and extraction mechanisms by systematically investigating the structure, surface properties, and defect vacancies of both doped and undoped manganese oxide sorbents.
Shuxuan Yan   +6 more
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Synthesis of noble metal-free monodisperse high-entropy oxides hollow nanocubes libraries via a coordination etching strategy

open access: yesNature Communications
High-entropy oxides (HEOs) consist of multiple principal metal cations and oxygen anions, which enhances compositional versatility and promotes the emergence of atypical properties within oxide materials.
Yuanting Lei   +14 more
doaj   +1 more source

Research Progress on Separation and Purification Technology of Quinoa Saponins

open access: yesLiang you shipin ke-ji
Quinoa saponins are a kind of pentacyclic triterpenoids with important physiological and pharmacological activities. Due to the wide variety and wide polarity span, the conventional purification and separation methods not only require a lot of work, but ...
ZHOU Xue-yong   +5 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Development of Nano-hybrid Cellulose Acetate/TiO2 Membrane for Eugenol Purification from Crude Clove Leaf Oil

open access: yesMATEC Web of Conferences, 2018
Chemical separation and purification are the important part of the chemical industry which consumes up to 70% energy cost. The separation technology such as distillation and absorption are well known in essential oil purification.
Kusworo Tutuk Djoko   +2 more
doaj   +1 more source

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