Results 121 to 130 of about 277,425 (303)
Purification of metallurgical-grade silicon by Sn-Si refining system with calcium addition
Purification of metallurgical-grade silicon (MG-Si) by a combination of solvent refining and super gravity separation and acid leaching has been studied.
Gong, Xuzhong +4 more
core
Co, Mn and Cu usually coexist in the leachate of waste lithium ion batteries (LIBs). Extraction and separation of Co2+, Cu2+ and Mn2+ from sodium sulfate media by bis(2,4,4-trimethylpentyl) phosphinic acid, 2-ethylhexyl phosphinic acid mono-2-ethylhexyl ...
Sui, Na +6 more
core +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Sedimentation-Based Separation and Purification of Solid Industrial Waste: A Case Study of Phosphogpusym. [PDF]
Hou S +7 more
europepmc +1 more source
MITF maintains genome stability in nonmelanocyte lineages
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Hydrogen Purification Technologies in the Context of Its Utilization
This publication explores current and prospective methods for hydrogen production and purification, with a strong emphasis on membrane-based technologies for purification and separation.
Anna Król +4 more
doaj +1 more source
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Efficient Separation and Purification Method for Recovering Valuable Elements from Bismuth Telluride Refrigeration Chip Waste. [PDF]
Zhu J +8 more
europepmc +1 more source

