Results 71 to 80 of about 281,045 (214)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Retracted: A Brief Talk on the Design of Biopharmaceutical Separation and Purification Technology Course. [PDF]

J Healthc Eng, 2023
Healthcare Engineering JO.
europepmc   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Structural Insights Into Aluminum‐Doped Manganese Dioxides as Promising Materials for Direct Lithium Extraction: Modeling and Mechanism Study

Advanced Materials Interfaces
This study aimed to provide new insights into lithium (Li) sorption and extraction mechanisms by systematically investigating the structure, surface properties, and defect vacancies of both doped and undoped manganese oxide sorbents.
Shuxuan Yan, Shaozhen Pei, Xiaodong Li, Zhongyan Luo, Xiangping Chen, Małgorzata Szlachta, Junhua Xu   +6 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Synthesis of noble metal-free monodisperse high-entropy oxides hollow nanocubes libraries via a coordination etching strategy

Nature Communications
High-entropy oxides (HEOs) consist of multiple principal metal cations and oxygen anions, which enhances compositional versatility and promotes the emergence of atypical properties within oxide materials.
Yuanting Lei, Huishan Shang, Guosheng Li, Lili Zhang, Zhiyi Sun, Xiaochen Wang, Yafei Zhao, Xu Xiang, Zhi Zheng, Xinchang Pang, Jianrong Zeng, Ning Zhang, Xiangwen Liu, Wenxing Chen, Bing Zhang   +14 more
doaj   +1 more source

Research Progress on Separation and Purification Technology of Quinoa Saponins

Liang you shipin ke-ji
Quinoa saponins are a kind of pentacyclic triterpenoids with important physiological and pharmacological activities. Due to the wide variety and wide polarity span, the conventional purification and separation methods not only require a lot of work, but ...
ZHOU Xue-yong, NIU Yan, YANG Li-yan, WEI Zuo-fu, ZHANG Li-hong, WU Bao-mei   +5 more
doaj   +1 more source

Compressible Separator and Catalyst for Simultaneous Separation and Purification of Emulsions and Aqueous Pollutants. [PDF]

ACS Omega, 2023
Kim HJ, Jung YJ, Son SH, Choi WS.
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source