Results 51 to 60 of about 9,236,417 (302)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Influence of different blowing parameters on flow control on an airfoil
Journal of Mechanical Engineering and Sciences, 2022 A numerical study on flow separation control is conducted for an airfoil with a blowing jet. In this regard, the effect of different parameters of air blowing on stall controlling and flow structure over NACA 0012 is followed.
Sarallah Abbasi
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Automatic load change coordinated control of air separation units
, 2019 An automatic load change coordinated control system is developed for strongly coupled and nonlinear air separation units. Firstly, a loosely coupled model is established to solve the tight coupling problem and a robust control strategy integrated with ...
Zhang, Xin +4 more
core +3 more sources
Antibodies, 2017 Downstream of pharmaceutical proteins, such as monoclonal antibodies, is mainly done by chromatography, where concentration determination of coeluting components presents a major problem.
Steffen Zobel-Roos +3 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Metabolites, 2023 The healthy growth of infants during early life is associated with lifelong consequences. Breastfeeding has positive impacts on reducing obesity risk, which is likely due to the varied components of breast milk, such as N-acetylneuraminic acid (Neu5Ac ...
Runze Ouyang +14 more
doaj +1 more source
Active Flow Separation Control on a High-Lift Wing-Body Configuration - Part 1: Baseline Flow and Constant Blowing [PDF]
, 2011 This paper describes the influence of grid resolution and turbulence modeling for a 3D transport aircraft in high lift configuration with massive flap separation.
Breitenstein, Wiebke +4 more
core
, 2022 Extractive distillation has great significance for the separation of ethylbenzene from C8 aromatic hydrocarbons. Herein, a distillation process for the separation of ethylbenzene was designed using methyl phenylacetate as an extractant.
Jiahai Ding +4 more
core +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source