Results 71 to 80 of about 2,836,243 (255)

Coal and Gangue Underground Pneumatic Separation Effect Evaluation Influenced by Different Airflow Directions

open access: yesAdvances in Materials Science and Engineering, 2016
Coal and gangue underground pneumatic separation is of key importance for green mining. Two kinds of arrangement schemes for high-pressure value used in pneumatic separation system are proposed in this study.
Kehong Zheng   +3 more
doaj   +1 more source

Spring Assisting Mechanism for Enhancing the Separation Performance of Digital Light Process 3D Printers

open access: yesIEEE Access, 2019
Separation has been a historic problem in digital light process 3D printing, which limits the capability of printing large areas. Over the years, methods for reducing separation force and improving printing quality have primarily relied on changing ...
Yu-Sheng Lin, Cheng-Jung Yang
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

A new method for minimum distance separation factor calculation based on particle swarm optimization algorithm

open access: yesPetroleum Research
Anti-collision technology for wellbores is integrated into both the pre-drilling design and real-time drilling monitoring of cluster wells, infill wells, and directional wells.
Hu Yin   +4 more
doaj   +1 more source

Niche Separation Increases With Genetic Distance Among Bloom-Forming Cyanobacteria

open access: yesFrontiers in Microbiology, 2018
Bacterial communities are composed of distinct groups of potentially interacting lineages, each thought to occupy a distinct ecological niche. It remains unclear, however, how quickly niche preference evolves and whether more closely related lineages are
Nicolas Tromas   +7 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

The impact of background and context on car distance estimation [PDF]

open access: yes, 2014
It is well established that people underestimate the distance to objects depicted in virtual environments and two-dimensional (2D) displays. The reasons for the underestimation are still not fully understood.
Zhang, Fan
core  

Home - About - Disclaimer - Privacy