Results 61 to 70 of about 4,640,138 (299)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
A Novel Vane-type Oil-water Separator
Shiyou jixie, 2020 In the late stage of oil well production, the water cut is getting higher and higher, which puts forward higher requirements for downhole oil-water separators. A new type of vane type oil-water separator is introduced.
Zhan Min +6 more
doaj
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Efficient Speech Separation with Differencing
Given an input audio signal where multiple speakers talk over each other, the goal of speech separation is to recover the original signals of each speaker. In this paper we propose a novel sequence modelling method called relative context based on differencing and use it for a speech separation architecture called RCSep. The main advantages of relative
Joel Rixen, Matthias Renz
openaire +2 more sources
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Известия высших учебных заведений: Проблемы энергетики, 2017 The article focuses on the gases cleaning various methods from the dispersed phase, that adversely affects on the holding of technological processes.
A. R. Iskhakov, M. M. Basharov
doaj +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Design and Simulation of Fluid Separator for CO2 Flooding under Slug Flow
Shiyou jixie, 2020 During the oil production with the method of CO2 injection, overpressure casing gas is usually discharged into the production pipeline intermittently, which leads to the increase of gas-liquid ratio of produced fluid and even the formation of slug flow ...
Wang Xin +4 more
doaj
Zanco Journal of Pure and Applied Sciences, 2019 In the recent years, based on the developments of fabricating superhydrophobic/superoleophobic nanostructured surfaces, using theses materials for oil-water liquid phases separation have been extensively studied.
Elmira Velayi, Reza Norouzbeigi
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source