Results 41 to 50 of about 590,817 (334)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

THE PRINCIPLE OF SEPARATION OF POWERS - CONSTITUTIONAL GUARANTEE [PDF]

open access: yesChallenges of the Knowledge Society, 2017
The principle of ensuring the legal bases of the State functioning is the fundamental principle of law which actually settles down the principle of separation of powers: legislative, executive and judicial power.
Emilian CIONGARU
doaj  

The Principle of the Separation of Powers: the Ontological Presumption of an Ideologeme

open access: yesBaltic Journal of Law & Politics, 2020
The theoretical materiality of the principle of the separation of powers is beyond doubt. This principle is inevitable in discourse on the constitutional framework of the state, democracy and the rule of law, and it has its own form of expression in ...
Mesonis Gediminas
doaj   +1 more source

Philanthrocapitalism and the Separation of Powers

open access: yesAnnual Review of Law and Social Science, 2021
This article discusses the rise of an approach to philanthropic giving known as philanthrocapitalism. I relate it to a new paradigm in management theory that has claimed that private profit making naturally aligns with improved public welfare. I show how
L. McGoey
semanticscholar   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Constitutional changes and the dilemmas of constitutionalism

open access: yesZbornik Radova Pravnog Fakulteta u Splitu, 2009
The need to develop constitutional mechanisms whose aim is to resolve fundamental relations in society demands the widest possible inclusion of all of society’s active participants in the discussion on the need to adopt or revise the Constitution.
Arsen Bačić
doaj  

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

The Constitutional Court of Croatia and the concept of Inherent powers [PDF]

open access: yesPravni Zapisi
The article examines the Croatian Constitutional Court's interpretive approach to the existence of its own "inherent" powers and their relationship to the powers enumerated in the Constitution.
Gardašević Đorđe, Jarak Niko
doaj   +1 more source

A ‘Non-Power’ Looks at Separation of Powers [PDF]

open access: yes, 1989
On April 6, 1989, Dean, Alan B. Morrison of George Washington Law, delivered the Georgetown Law Center’s ninth Annual Philip A. Hart Memorial Lecture: A ‘Non-Power’ Looks at Separation of Powers.
Morrison, Alan B.
core   +1 more source

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