Pareto-Driven Multiobjective Design of Axial-Flow Automotive Fan with Response Surface Modeling. [PDF]
Ren K +5 more
europepmc +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Comparative evaluation of a basic life support educational model in non-health university students: the "<i>Lives to Give Life</i>" project and its social and health impact. [PDF]
Fernández Florido P +5 more
europepmc +1 more source
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha +4 more
wiley +1 more source
Minimising event size, maximising physics: inclusive particle isolation for LHCb's Run 3. [PDF]
Calvi M +14 more
europepmc +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Pulmonary artery floating sign: a novel predictor of fatal haemoptysis in pulmonary mucormycosis and its early intervention strategy. [PDF]
Yu M +10 more
europepmc +1 more source
Management and outcomes in women and men weaning from invasive mechanical ventilation: insights from the WEAN SAFE study. [PDF]
Caldecott R +14 more
europepmc +1 more source
Joint models targeting U.S. Army soldiers at high-risk of post-separation unemployment, homelessness, and suicide-related behaviors. [PDF]
Borowski S +16 more
europepmc +1 more source

