Multidimensional Structural Echocardiographic Patterns and Risk Score for Prognostic Stratification in Ischemic Cardiomyopathy. [PDF]
Tang R +7 more
europepmc +1 more source
A Generalization of the Method of Separation of Variables [PDF]
openaire +2 more sources
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Cluster-Defined Metabolic Heterogeneity and Longitudinal Effects of Allopurinol and SGLT2 Inhibitors in Hyperuricemic Type 2 Diabetes. [PDF]
Fejes R +3 more
europepmc +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Experimental Design-Based Dispersive Liquid-Liquid Microextraction with GC-FID for Determination of Polycyclic Aromatic Hydrocarbons in Surface Water. [PDF]
Minghong C +5 more
europepmc +1 more source
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
Integrated comprehensive assessment for predicting weaning success in difficult-to-wean critically ill patients: the WEAN-US study. [PDF]
Fogagnolo A +11 more
europepmc +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Machine Learning-Derived Risk Groups and Clinical Implementation of Survival Prediction in Lung Cancer: Evidence from a Kazakh National Cohort. [PDF]
Avizova Z, Myssayev AO, Iztleuov YM.
europepmc +1 more source

