Results 91 to 100 of about 9,530,700 (298)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Evaluation of sample preparation approaches and separation parameters in HPLC of plant bioactive compounds

open access: yes, 2015
Plant bioactive compounds can be defined as secondary plant metabolites produced within the plants besides the primary biosynthetic and metabolic routes.
Isabella Nicoletti   +3 more
core  

Recent Developments of Graphene Oxide-Based Membranes: A Review

open access: yesMembranes, 2017
Membrane-based separation technology has attracted great interest in many separation fields due to its advantages of easy-operation, energy-efficiency, easy scale-up, and environmental friendliness.
Jinxia Ma, Dan Ping, Xinfa Dong
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Two-Fund separation and positive marginal utility [PDF]

open access: yes
The requirement of positive marginal utility only makes it possible to derive a restricted twofund separation theorem for portfolio selection problems replacing the original separation theorem of Cass and Stiglitz (1970).
Gürtler, Marc, Breuer, Wolfgang
core  

Performance Analysis of Central-Axial Hydrocyclone for Oil-Water Separation

open access: yesShiyou jixie
The single-well injection and production technology separates oil and water from high water-cut produced fluid in the wellbore,and the hydrocyclone is a key equipment for the efficient operation of this technology.To further improve the downhole oil ...
Li Weiwei   +6 more
doaj  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

UiO-66 Metal-Organic Framework Membranes: Structural Engineering for Separation Applications

open access: yesMembranes
Metal-organic frameworks (MOFs) have been recognized as promising materials for membrane-based separation technologies due to their exceptional porosity, structural tunability, and chemical stability.
Yanwei Sun
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

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