Results 91 to 100 of about 473,299 (218)

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Attapulgite Nanorod-Incorporated Polyimide Membrane for Enhanced Gas Separation Performance. [PDF]

open access: yesPolymers (Basel), 2022
Zhang S   +8 more
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Study on Spacing Regulation and Separation Performance of Nanofiltration Membranes of GO. [PDF]

open access: yesMembranes (Basel), 2022
Meng N   +7 more
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Ultra-performance polymer separations

open access: yes, 2012
Vloeistofchromatografie (liquid chromatography, LC) is een analytische techniek waarmee het mogelijk is een monster te scheiden in verschillende componenten. Het scheidingsprincipe van LC is gebaseerd op niet-gelijke verdeling van moleculen over een stationaire en een mobiele fase.
openaire   +1 more source

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