Results 81 to 90 of about 573,828 (318)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Lightweight target speaker separation network based on joint training
EURASIP Journal on Audio, Speech, and Music Processing, 2023 Target speaker separation aims to separate the speech components of the target speaker from mixed speech and remove extraneous components such as noise.
Jing Wang +5 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Influence of Separation Chamber Structure on Separation Performance of Downhole Hydrocyclone
Shiyou jixie, 2019 To obtain the best separation performance of hydrocyclone, the flow field characteristics and separation performance of the starting-taper hydrocyclone and back-taper hydrocyclone are analyzed using numerical simulation method by changing the inlet ...
Zhang Yong +3 more
doaj
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Frontiers in Chemistry, 2020 A novel monohydroxycucurbit[7]uril-based stationary phase for capillary gas chromatography (GC) has been produced. For this, a capillary column coating was made using a sol–gel technique, incorporating synthesized monohydroxycucurbit[7]uril [(OH)Q[7 ...
Jing He +7 more
doaj +1 more source
AIP Advances, 2022 A numerical investigation of the aerodynamic separation associated with converging–diverging two-dimensional planar micronozzles is reported. The impact of divergent section shapes such as linear, bell, and trumpet, the effect of different back pressure ...
Manu K Sukesan, Shine S R
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Energies, 2019 The application of a hydrocyclone to recycle NGH and desand during NGH exploitation is a novel idea. The flow field and performance of this hydrocyclone is in the frontier of the research in this field and is unclear so far. This research aimed to reveal
Shunzuo Qiu +3 more
doaj +1 more source