Results 181 to 190 of about 573,828 (318)

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Evaluation of Surface Properties and Separation Performance of NF and RO Membranes for Phthalates Removal. [PDF]

open access: yesMembranes (Basel), 2023
Lim EQ   +6 more
europepmc   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Attapulgite Nanorod-Incorporated Polyimide Membrane for Enhanced Gas Separation Performance. [PDF]

open access: yesPolymers (Basel), 2022
Zhang S   +8 more
europepmc   +1 more source

Ultra-performance polymer separations

open access: yes, 2012
Vloeistofchromatografie (liquid chromatography, LC) is een analytische techniek waarmee het mogelijk is een monster te scheiden in verschillende componenten. Het scheidingsprincipe van LC is gebaseerd op niet-gelijke verdeling van moleculen over een stationaire en een mobiele fase.
openaire   +1 more source

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